Potent upregulation of glutathione and NAD(P)H:quinone oxidoreductase 1 by alpha-lipoic acid in human neuroblastoma SH-SY5Y cells: protection against neurotoxicant-elicited cytotoxicity (Q40066980)

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English	Potent upregulation of glutathione and NAD(P)H:quinone oxidoreductase 1 by alpha-lipoic acid in human neuroblastoma SH-SY5Y cells: protection against neurotoxicant-elicited cytotoxicity	scientific article

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scholarly article

1 reference

Europe PubMed Central

17 September 2017

Potent upregulation of glutathione and NAD(P)H:quinone oxidoreductase 1 by alpha-lipoic acid in human neuroblastoma SH-SY5Y cells: protection against neurotoxicant-elicited cytotoxicity (English)

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Europe PubMed Central

17 September 2017

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author name string

Zhenquan Jia

1

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Europe PubMed Central

17 September 2017

Seema Hallur

2

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Europe PubMed Central

17 September 2017

Hong Zhu

3

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Europe PubMed Central

17 September 2017

Yunbo Li

4

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Europe PubMed Central

17 September 2017

Hara P Misra

5

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Europe PubMed Central

17 September 2017

language of work or name

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publication date

17 October 2007

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Europe PubMed Central

17 September 2017

Neurochemical Research

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Europe PubMed Central

17 September 2017

33

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Europe PubMed Central

17 September 2017

5

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Europe PubMed Central

17 September 2017

790-800

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Europe PubMed Central

17 September 2017

https://scigraph.springernature.com/pub.10.1007/s11064-007-9496-5

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Oxidative stress and nitration in neurodegeneration: cause, effect, or association?

1 reference

https://api.crossref.org/works/10.1007%2FS11064-007-9496-5

21 January 2018

The pharmacology of the antioxidant lipoic acid

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21 January 2018

Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species.

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12 December 2020

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The Role of Chemically Induced Glutathione and Glutathione S-Transferase in Protecting Against 4-Hydroxy-2-Nonenal- Mediated Cytotoxicity in Vascular Smooth Muscle Cells

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12 December 2020

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Alpha-lipoic acid: a metabolic antioxidant and potential redox modulator of transcription.

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https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

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Prevention of hypertension, insulin resistance, and oxidative stress by alpha-lipoic acid

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12 December 2020

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Peroxynitrite in the pathogenesis of Parkinson's disease and the neuroprotective role of metallothioneins

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12 December 2020

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Investigations on the pharmacokinetics of alpha-lipoic acid in healthy volunteers

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12 December 2020

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Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention

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12 December 2020

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Neuroprotection by the metabolic antioxidant alpha-lipoic acid

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12 December 2020

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Dose-proportionality of oral thioctic acid--coincidence of assessments via pooled plasma and individual data

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Induction of cellular glutathione and glutathione S-transferase by 3H-1,2-dithiole-3-thione in rat aortic smooth muscle A10 cells: protection against acrolein-induced toxicity

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12 December 2020

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Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage

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12 December 2020

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Structure-activity relationships for growth inhibition and induction of apoptosis by 4-hydroxy-2-nonenal in raw 264.7 cells

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12 December 2020

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Glutathione: an overview of biosynthesis and modulation

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12 December 2020

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Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial.

1 reference

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12 December 2020

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Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

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Parkinson's disease: clinical signs and symptoms, neural mechanisms, positron emission tomography, and therapeutic interventions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2 controls bone marrow stromal cell susceptibility to oxidative and electrophilic stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

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Induction of endogenous glutathione by the chemoprotective agent, 3H-1,2-dithiole-3-thione, in human neuroblastoma SH-SY5Y cells affords protection against peroxynitrite-induced cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catalase in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

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Reactive oxygen species and reactive nitrogen species: relevance to cyto(neuro)toxic events and neurologic disorders. An overview.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

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Glutathione transferases

1 reference

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12 December 2020

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Upregulation of endogenous glutathione system by 3H-1,2-dithiole-3-thione in pancreatic RINm5F beta-cells as a novel strategy for protecting against oxidative beta-cell injury

1 reference

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12 December 2020

based on heuristic

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4-hydroxynonenal as a bioactive marker of pathophysiological processes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

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Alpha-lipoic acid differently affects the reserpine-induced oxidative stress in the striatum and prefrontal cortex of rat brain.

1 reference

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12 December 2020

based on heuristic

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The molecular effects of acrolein

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https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

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Glutathione S-transferases. The first enzymatic step in mercapturic acid formation

1 reference

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12 December 2020

based on heuristic

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Oxidation of ubiquinol by peroxynitrite: implications for protection of mitochondria against nitrosative damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effects of alpha-lipoic acid and its enantiomers demonstrated in rodent models of focal cerebral ischemia.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione and catalase provide overlapping defenses for protection against hydrogen peroxide in the yeast Saccharomyces cerevisiae.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

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A comparison between the antioxidant and peroxynitrite-scavenging functions of the vitamin E metabolites alpha- and gamma-carboxyethyl-6-hydroxychromans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

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Antioxidants and phase 2 enzymes in cardiomyocytes: Chemical inducibility and chemoprotection against oxidant and simulated ischemia-reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

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Glutathione Peroxidase Protects against Peroxynitrite-mediated Oxidations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-lipoic acid: a multifunctional antioxidant that improves insulin sensitivity in patients with type 2 diabetes

1 reference

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12 December 2020

based on heuristic

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Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

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Alpha-lipoic acid inhibits glycogen synthesis in rat soleus muscle via its oxidative activity and the uncoupling of mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

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Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity

1 reference

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12 December 2020

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Possible roles of nitric oxide in the physiology and pathophysiology of the mammalian cochlea

1 reference

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Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

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Pesticide exposure on southwestern Taiwanese with MnSOD and NQO1 polymorphisms is associated with increased risk of Parkinson's disease

1 reference

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12 December 2020

based on heuristic

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NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effects of alpha-lipoic acid and its positively charged amide analogue

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Automated assays for superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a melanocyte phenotype in human neuroblastoma cells in vitro

1 reference

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12 December 2020

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Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP and cyclic GMP independent stimulation of ventricular calcium current by peroxynitrite donors in guinea pig myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fluorometric method for determination of oxidized and reduced glutathione in tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinone reductases multitasking in the metabolic world

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-lipoic acid does not acutely affect resistance and conduit artery function or oxidative stress in healthy men.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assays of glutathione peroxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

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inferred from PubMed ID database lookup

Free radicals as mediators of tissue injury and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

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Long-term safety of alpha-lipoic acid (ALA) consumption: A 2-year study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple pathways of peroxynitrite cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pain and sensory symptoms in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

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Coenzyme Q10: a review of its promise as a neuroprotectant.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress as a cause of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reduction of alpha-tocopherolquinone by human NAD(P)H: quinone oxidoreductase: the role of alpha-tocopherolhydroquinone as a cellular antioxidant

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An assay for superoxide dismutase activity in mammalian tissue homogenates

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoic acid increases glutathione production and enhances the effect of mercury in human cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11064-007-9496-5

1 reference

Europe PubMed Central

17 September 2017

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1 reference

Europe PubMed Central

17 September 2017

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