Hyperpolarization-activated cyclic nucleotide-modulated 'HCN' channels confer regular and faster rhythmicity to beating mouse embryonic stem cells. (Q40046024)

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scientific article published on 22 November 2007

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English	Hyperpolarization-activated cyclic nucleotide-modulated 'HCN' channels confer regular and faster rhythmicity to beating mouse embryonic stem cells.	scientific article published on 22 November 2007

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scholarly article

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27 December 2019

Hyperpolarization-activated cyclic nucleotide-modulated 'HCN' channels confer regular and faster rhythmicity to beating mouse embryonic stem cells (English)

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27 December 2019

Leif Hove-Madsen

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27 December 2019

Glen F. Tibbits

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27 December 2019

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Yang Qu

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27 December 2019

Gina M Whitaker

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27 December 2019

Eric A Accili

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27 December 2019

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22 November 2007

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27 December 2019

Journal of Physiology

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27 December 2019

586

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27 December 2019

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27 December 2019

701-716

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27 December 2019

HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375615

30 August 2018

HCN2 and HCN4 isoforms self-assemble and co-assemble with equal preference to form functional pacemaker channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375615

30 August 2018

Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach.

1 reference

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30 August 2018

The emergence of a general theory of the initiation and strength of the heartbeat

1 reference

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30 August 2018

Electrophysiological properties of pluripotent human and mouse embryonic stem cells

1 reference

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30 August 2018

The murine HCN3 gene encodes a hyperpolarization-activated cation channel with slow kinetics and unique response to cyclic nucleotides

1 reference

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30 August 2018

Initiation of embryonic cardiac pacemaker activity by inositol 1,4,5-trisphosphate-dependent calcium signaling

1 reference

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30 August 2018

Identification and characterization of embryonic stem cell-derived pacemaker and atrial cardiomyocytes

1 reference

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30 August 2018

Structural elements of instantaneous and slow gating in hyperpolarization-activated cyclic nucleotide-gated channels

1 reference

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30 August 2018

The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart

1 reference

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30 August 2018

NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function

1 reference

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30 August 2018

Characterization and regulation of T-type Ca2+ channels in embryonic stem cell-derived cardiomyocytes

1 reference

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30 August 2018

Development of electrical activity in cardiac myocyte aggregates derived from mouse embryonic stem cells

1 reference

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30 August 2018

Hyperpolarization-activated cation currents: from molecules to physiological function

1 reference

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30 August 2018

Stem cell-derived cardiomyocytes demonstrate arrhythmic potential

1 reference

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30 August 2018

Separable gating mechanisms in a Mammalian pacemaker channel.

1 reference

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30 August 2018

From funny current to HCN channels: 20 years of excitation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375615

30 August 2018

Pacemaker channels produce an instantaneous current.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375615

30 August 2018

Ontogeny of humoral heart rate regulation in the embryonic mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375615

30 August 2018

Sinoatrial nodal cell ryanodine receptor and Na(+)-Ca(2+) exchanger: molecular partners in pacemaker regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375615

30 August 2018

Integrated allosteric model of voltage gating of HCN channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375615

30 August 2018

I(f) current and spontaneous activity in mouse embryonic ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375615

30 August 2018

Molecular and functional heterogeneity of hyperpolarization-activated pacemaker channels in the mouse CNS.

1 reference

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30 August 2018

Functional expression and regulation of the hyperpolarization activated non-selective cation current in embryonic stem cell-derived cardiomyocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375615

30 August 2018

Intracellular Ca2+ oscillations drive spontaneous contractions in cardiomyocytes during early development

1 reference

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30 August 2018

A TTX-sensitive inward sodium current contributes to spontaneous activity in newborn rabbit sino-atrial node cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375615

30 August 2018

Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts

1 reference

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30 August 2018

Cardiac pacemaking in the sinoatrial node

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30 August 2018

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

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30 August 2018

Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375615

30 August 2018

Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents

1 reference

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30 August 2018

Pacemaker mechanisms in cardiac tissue.

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30 August 2018

Pluripotent mouse embryonic stem cells are able to differentiate into cardiomyocytes expressing chronotropic responses to adrenergic and cholinergic agents and Ca2+ channel blockers

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30 August 2018

Mouse embryonic stem cells express the cardiac myosin heavy chain genes during development in vitro

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30 August 2018

Background current in sino‐atrial node cells of the rabbit heart

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30 August 2018

Reciprocal role of the inward currents ib, Na and i(f) in controlling and stabilizing pacemaker frequency of rabbit sino-atrial node cells

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30 August 2018

Properties of the hyperpolarizing-activated current (if) in cells isolated from the rabbit sino-atrial node

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21 January 2018

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2 December 2018

Embryonic stem cells form an organized, functional cardiac conduction system in vitro

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study of the ionic nature of the pace-maker current in calf Purkinje fibres

1 reference

https://pubmed.ncbi.nlm.nih.gov/18033814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential control of the hyperpolarization-activated current (i(f)) by cAMP gating and phosphatase inhibition in rabbit sino-atrial node myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18033814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1113/JPHYSIOL.2007.144329

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18033814%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

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Europe PubMed Central

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27 December 2019

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