Metabotropic glutamate receptors regulate differentiation of embryonic stem cells into GABAergic neurons (Q40028395)

16 September 2017

title

Metabotropic glutamate receptors regulate differentiation of embryonic stem cells into GABAergic neurons (English)

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16 September 2017

P Sale

6

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Giuseppe Battaglia

object named as

G Battaglia

8

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Fabrizio Stocchi

object named as

F Stocchi

7

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author name string

I Sarichelou

1

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16 September 2017

I Cappuccio

2

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16 September 2017

F Ferranti

3

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16 September 2017

P Mosillo

4

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16 September 2017

C Ciceroni

5

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16 September 2017

F Nicoletti

9

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16 September 2017

D Melchiorri

10

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16 September 2017

publication date

4 January 2008

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Cell Death & Differentiation

16 September 2017

published in

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16 September 2017

volume

15

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16 September 2017

issue

4

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16 September 2017

page(s)

700-707

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402298

16 September 2017

exact match

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cites work

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The mGlu5 metabotropic glutamate receptor is expressed in zones of active neurogenesis of the embryonic and postnatal brain

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Glutamate and GABA receptor signalling in the developing brain.

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PHCCC, a specific enhancer of type 4 metabotropic glutamate receptors, reduces proliferation and promotes differentiation of cerebellar granule cell neuroprecursors.

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Endogenous activation of metabotropic glutamate receptors supports the proliferation and survival of neural progenitor cells.

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Metabotropic glutamate receptors are expressed in adult human glial progenitor cells.

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Oligodendroglial metabotropic glutamate receptors are developmentally regulated and involved in the prevention of apoptosis.

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Glutamate signalling in non-neuronal tissues

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Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo.

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Pharmacological activation of mGlu4 metabotropic glutamate receptors inhibits the growth of medulloblastomas.

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Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.

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Metabotropic glutamate receptor 4 expression in colorectal carcinoma and its prognostic significance

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Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer

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Molecular determinants of metabotropic glutamate receptor signaling.

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Endogenous activation of mGlu5 metabotropic glutamate receptors supports self-renewal of cultured mouse embryonic stem cells.

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Endogenously activated mGlu5 metabotropic glutamate receptors sustain the increase in c-Myc expression induced by leukaemia inhibitory factor in cultured mouse embryonic stem cells.

21 January 2018

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Context-dependent regulation of embryonic stem cell differentiation by mGlu4 metabotropic glutamate receptors.

21 January 2018

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Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture

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Embryonic stem cell-derived neurogenesis. Retinoic acid induction and lineage selection of neuronal cells.

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Differentiation of mouse embryonic stem cells into a defined neuronal lineage

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Cell replacement therapies for central nervous system disorders.

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Methoxyphenylethynyl, methoxypyridylethynyl and phenylethynyl derivatives of pyridine: synthesis, radiolabeling and evaluation of new PET ligands for metabotropic glutamate subtype 5 receptors

21 January 2018

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Insulin secretion is controlled by mGlu5 metabotropic glutamate receptors

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Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

21 January 2018

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Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity

21 January 2018

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The metabotropic glutamate receptor 5 antagonist MPEP and the mGluR2 agonist LY379268 modify disease progression in a transgenic mouse model of Huntington's disease

21 January 2018

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Retinoic acid promotes neural and represses mesodermal gene expression in mouse embryonic stem cells in culture.

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Distribution of metabotropic glutamate receptor 7 messenger RNA in the developing and adult rat brain

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7 January 2021

The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate recepto

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7 January 2021

Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4.

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7 January 2021

Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective

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7 January 2021

Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity.

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402298

1 reference

Dimensions Publication ID

16 September 2017

1051935849

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1 reference