Differential control of CXCR4 and CD4 downregulation by HIV-1 Gag. (Q40014256)

16 September 2017

Differential control of CXCR4 and CD4 downregulation by HIV-1 Gag. (English)

1 reference

16 September 2017

Rajeshwari R Valiathan

series ordinal

1

object named as

Rajeshwari R Valiathan

1 reference

16 September 2017

Marilyn D Resh

2

1 reference

16 September 2017

11 February 2008

1 reference

16 September 2017

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16 September 2017

5

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16 September 2017

23

1 reference

https://scigraph.springernature.com/pub.10.1186/1743-422x-5-23

16 September 2017

0 references

cites work

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Regulation of CXCR4 signaling

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Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release

22 September 2017

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Expression of Nef downregulates CXCR4, the major coreceptor of human immunodeficiency virus, from the surfaces of target cells and thereby enhances resistance to superinfection

22 September 2017

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Contribution of Vpu, Env, and Nef to CD4 down-modulation and resistance of human immunodeficiency virus type 1-infected T cells to superinfection

22 September 2017

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Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways

22 September 2017

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The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.

22 September 2017

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A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis

22 September 2017

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Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity

22 September 2017

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HIV and the chemokine system: 10 years later

22 September 2017

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An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexins

22 September 2017

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Late budding domains and host proteins in enveloped virus release

22 September 2017

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HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent

22 September 2017

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Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1.

22 September 2017

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22 September 2017

A protein's final ESCRT.

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Expression of human immunodeficiency virus type 1 gag modulates ligand-induced downregulation of EGF receptor

22 September 2017

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The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation

22 September 2017

1 reference

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Role of CD4 receptor down-regulation during HIV-1 infection

22 September 2017

1 reference

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The physiological relevance of CD4 receptor down-modulation during HIV infection

22 September 2017

1 reference

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Role of mammalian vacuolar protein-sorting proteins in endocytic trafficking of a non-ubiquitinated G protein-coupled receptor to lysosomes

22 September 2017

1 reference

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Stable gene silencing in human monocytic cell lines using lentiviral-delivered small interference RNA. Silencing of the p110alpha isoform of phosphoinositide 3-kinase reveals differential regulation of adherence induced by 1alpha,25-dihydroxycholeca

22 September 2017

1 reference

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The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4

22 September 2017

1 reference

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Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins

22 September 2017

1 reference

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The Protein Network of HIV Budding

22 September 2017

1 reference

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AIP1/ALIX Is a Binding Partner for HIV-1 p6 and EIAV p9 Functioning in Virus Budding

22 September 2017

1 reference

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Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein.

22 September 2017

1 reference

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Protein sorting into multivesicular endosomes

22 September 2017

1 reference

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The ins and outs of G protein-coupled receptor trafficking

22 September 2017

1 reference

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Defects in human immunodeficiency virus budding and endosomal sorting induced by TSG101 overexpression.

22 September 2017

1 reference

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In vivo evolution of human immunodeficiency virus type 1 toward increased pathogenicity through CXCR4-mediated killing of uninfected CD4 T cells

22 September 2017

1 reference

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Myristoylation as a target for inhibiting HIV assembly: unsaturated fatty acids block viral budding

22 September 2017

1 reference

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Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival

22 September 2017

1 reference

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Signal transduction and endocytosis: close encounters of many kinds

22 September 2017

1 reference

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Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag)

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

CXCR4 is down-regulated in cells infected with the CD4-independent X4 human immunodeficiency virus type 1 isolate m7NDK

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Localization of human immunodeficiency virus type 1 Gag and Env at the plasma membrane by confocal imaging

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Kinetic analysis of human immunodeficiency virus type 1 assembly reveals the presence of sequential intermediates

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-kappaB

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Spontaneous and ligand-induced trafficking of CXC-chemokine receptor 4.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Chemokines--chemotactic cytokines that mediate inflammation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Inhibition of Nef- and phorbol ester-induced CD4 degradation by macrolide antibiotics.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

T-lymphocyte activation: the role of protein kinase C and the bifurcating inositol phospholipid signal transduction pathway

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Human immunodeficiency virus (HIV) type 1 can superinfect HIV-2-infected cells: pseudotype virions produced with expanded cellular host range

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Human immunodeficiency virus type 1 Gag contains a dileucine-like motif that regulates association with multivesicular bodies

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Association of p56lck with the cytoplasmic domain of CD4 modulates HIV-1 expression.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Phosphorylation-dependent down-modulation of CD4 requires a specific structure within the cytoplasmic domain of CD4.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Internalization, lysosomal degradation and new synthesis of surface membrane CD4 in phorbol ester-activated T-lymphocytes and U-937 cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Degradation of CD4 following phorbol-induced internalization in human T lymphocytes. Evidence for distinct endocytic routing of CD4 and CD3

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

ARF1 regulates Nef-induced CD4 degradation.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Dynamics of cytokine expression in HIV productively infected primary CD4+ T cells.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

Cell surface CD4 inhibits HIV-1 particle release by interfering with Vpu activity.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262066

The role of receptor kinases and arrestins in G protein-coupled receptor regulation

20 August 2018

1 reference

12 December 2020

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

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12 December 2020

Rapid phosphorylation and modulation of the T4 antigen on cloned helper T cells induced by phorbol myristate acetate or antigen

1 reference

12 December 2020

Modulation of CD4 by antigenic activation

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12 December 2020

Phosphorylation of T cell membrane proteins by activators of protein kinase C

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12 December 2020

Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen

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12 December 2020

Identifiers

DOI

10.1186/1743-422X-5-23

1 reference

PMCID

2262066

Dimensions Publication ID

16 September 2017

0 references

1 reference

16 September 2017

1 reference

PMCID

2262066