Bidirectional promoter interference between two widely used internal heterologous promoters in a late-generation lentiviral construct (Q40011728)

16 September 2017

Bidirectional promoter interference between two widely used internal heterologous promoters in a late-generation lentiviral construct (English)

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16 September 2017

J A Curtin

1

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16 September 2017

A P Dane

2

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16 September 2017

A Swanson

3

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16 September 2017

I E Alexander

4

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16 September 2017

S L Ginn

5

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16 September 2017

24 January 2008

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16 September 2017

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16 September 2017

15

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16 September 2017

5

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16 September 2017

384-390

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3303105

16 September 2017

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Recombinant AAV vectors containing the foot and mouth disease virus 2A sequence confer efficient bicistronic gene expression in cultured cells and rat substantia nigra neurons

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Transcriptional interference by independently regulated genes occurs in any relative arrangement of the genes and is influenced by chromosomal integration position

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Transcriptional interference in avian retroviruses—implications for the promoter insertion model of leukaemogenesis

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Transcription start regions in the human genome are favored targets for MLV integration

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Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells

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Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter.

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Two Sp1/Sp3 binding sites in the major immediate-early proximal enhancer of human cytomegalovirus have a significant role in viral replication

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Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes in vitro

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Insulators: exploiting transcriptional and epigenetic mechanisms

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Genomic insulators: connecting properties to mechanism

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Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

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Limiting {gamma}c expression differentially affects signaling via the interleukin (IL)-7 and IL-15 receptors

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High-frequency deletion in recovered retrovirus vectors containing exogenous DNA with promoters

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Internal initiation of translation in retroviral vectors carrying picornavirus 5' nontranslated regions.

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Identifiers

DOI

10.1038/SJ.GT.3303105

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Dimensions Publication ID

16 September 2017

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