Rb function is required for E1A-induced S-phase checkpoint activation (Q39986158)

16 September 2017

Rb function is required for E1A-induced S-phase checkpoint activation (English)

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16 September 2017

A Nemajerova

1

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16 September 2017

F Talos

series ordinal

2

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16 September 2017

U M Moll

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3

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16 September 2017

O Petrenko

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4

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16 September 2017

2 May 2008

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Cell Death & Differentiation

16 September 2017

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16 September 2017

15

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16 September 2017

9

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16 September 2017

1440-1449

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https://scigraph.springernature.com/pub.10.1038/cdd.2008.66

16 September 2017

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Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

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Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells.

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Cellular targets for transformation by the adenovirus E1A proteins

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E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

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Adenovirus-5 E1A: paradox and paradigm

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Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor

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The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F

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7 January 2021

The E2F transcription factor is a cellular target for the RB protein

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7 January 2021

Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F.

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Macrophage migration inhibitory factor MIF interferes with the Rb-E2F pathway

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G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment

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Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

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Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

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E1A signaling to p53 involves the p19(ARF) tumor suppressor

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A p53-dependent mouse spindle checkpoint

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The Rb/E2F pathway: expanding roles and emerging paradigms

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7 January 2021

Molecular mechanisms of E2F-dependent activation and pRB-mediated repression

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7 January 2021

The retinoblastoma protein regulates pericentric heterochromatin

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7 January 2021

An E2F binding-deficient Rb1 protein partially rescues developmental defects associated with Rb1 nullizygosity

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7 January 2021

The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

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Regulation of E2F through ubiquitin-proteasome-dependent degradation: stabilization by the pRB tumor suppressor protein

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Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins

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Stabilization of p53 by adenovirus E1A occurs through its amino-terminal region by modification of the ubiquitin-proteasome pathway

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Regulation of the 26S proteasome by adenovirus E1A

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The targeting of the proteasomal regulatory subunit S2 by adenovirus E1A causes inhibition of proteasomal activity and increased p53 expression

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7 January 2021

Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins

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7 January 2021

On the road to cancer: aneuploidy and the mitotic checkpoint

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7 January 2021

Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells.

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7 January 2021

A viral mechanism for remodeling chromatin structure in G0 cells

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7 January 2021

Active Localization of the Retinoblastoma Protein in Chromatin and Its Response to S Phase DNA Damage

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7 January 2021

Emerging roles for E2F: Beyond the G1/S transition and DNA replication

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Nuclear organization of DNA replication in primary mammalian cells.

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7 January 2021

gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

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7 January 2021

Escape from premature senescence is not sufficient for oncogenic transformation by Ras.

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7 January 2021

Re-evaluating cell-cycle regulation by E2Fs.

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7 January 2021

Target gene specificity of E2F and pocket protein family members in living cells

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7 January 2021

Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

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7 January 2021

pRB-E2F1 complexes are resistant to adenovirus E1A-mediated disruption

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7 January 2021

Identifiers

DOI

10.1038/CDD.2008.66

1 reference

16 September 2017

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