Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas. (Q39983693)

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English	Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas.	scientific article

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7 January 2020

Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas (English)

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Anthony Tak-Cheung Chan

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K Y Lee

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H Geng

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K M Ng

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J Yu

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A van Hasselt

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Y Cao

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Y-X Zeng

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A H Y Wong

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X Wang

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J Ying

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G Srivastava

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L-D Wang

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T T Kwok

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B-Z Levi

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12 May 2008

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5267-5276

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https://scigraph.springernature.com/pub.10.1038/onc.2008.147

0 references

IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression

1 reference

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21 January 2018

Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Interferon regulatory factor-1 (IRF-1) exhibits tumor suppressor activities in breast cancer associated with caspase activation and induction of apoptosis

1 reference

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31 March 2020

Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Establishment and characterization of three transplantable EBV-containing nasopharyngeal carcinomas

1 reference

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31 March 2020

Evaluation of hypermethylated tumor suppressor genes as tumor markers in mouth and throat rinsing fluid, nasopharyngeal swab and peripheral blood of nasopharygeal carcinoma patient

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Interferon-gamma induces regression of epithelial cell carcinoma: critical roles of IRF-1 and ICSBP transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

A truncated IFN-regulatory factor-8\IFN consensus sequence-binding protein acts as dominant-negative, interferes with endogenous protein-protein interactions and leads to apoptosis of immune cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene

1 reference

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31 March 2020

Signaling through IFN regulatory factor-5 sensitizes p53-deficient tumors to DNA damage-induced apoptosis and cell death

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

The fundamental role of epigenetic events in cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Two genetic hits (more or less) to cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Focus on nasopharyngeal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

THY1 is a candidate tumour suppressor gene with decreased expression in metastatic nasopharyngeal carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

TSLC1 is a tumor suppressor gene associated with metastasis in nasopharyngeal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

The growing family of interferon regulatory factors.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

The interferon regulatory factor ICSBP/IRF-8 in combination with PU.1 up-regulates expression of tumor suppressor p15(Ink4b) in murine myeloid cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

TSLC1 gene silencing in cervical cancer cell lines and cervical neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Aberrant methylation of CDH13 gene in nasopharyngeal carcinoma could serve as a potential diagnostic biomarker

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

ICSBP/IRF-8 inhibits mitogenic activity of p210 Bcr/Abl in differentiating myeloid progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

ICSBP/IRF-8: its regulatory roles in the development of myeloid cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Nasopharyngeal carcinoma: molecular pathogenesis and therapeutic developments

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Establishment of two immortalized nasopharyngeal epithelial cell lines using SV40 large T and HPV16E6/E7 viral oncogenes.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Ad-IRF-1 induces apoptosis in esophageal adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/beta-catenin signaling, and is frequently methylated in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

The interferon consensus sequence-binding protein activates transcription of the gene encoding neurofibromin 1

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.147

31 March 2020

Identifiers

10.1038/ONC.2008.147

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7 January 2020

1 reference

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7 January 2020

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