Targeted inhibition of platelet-derived growth factor receptor-beta subunit in hepatic stellate cells ameliorates hepatic fibrosis in rats (Q39977440)

16 September 2017

title

Targeted inhibition of platelet-derived growth factor receptor-beta subunit in hepatic stellate cells ameliorates hepatic fibrosis in rats (English)

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16 September 2017

S-W Chen

1

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16 September 2017

Y-X Chen

2

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16 September 2017

X-R Zhang

3

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16 September 2017

H Qian

4

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16 September 2017

W-Z Chen

5

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16 September 2017

W-F Xie

6

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16 September 2017

publication date

29 May 2008

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16 September 2017

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16 September 2017

volume

15

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16 September 2017

issue

21

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16 September 2017

page(s)

1424-1435

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https://scigraph.springernature.com/pub.10.1038/gt.2008.93

16 September 2017

exact match

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cites work

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Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture

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Gene therapy of liver diseases

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Antisense strategy against PDGF B-chain proves effective in preventing experimental liver fibrogenesis

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Effects of the tyrosine protein kinase inhibitor genistein on the proliferation, activation of cultured rat hepatic stellate cells

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Imatinib mesylate (STI-571) attenuates liver fibrosis development in rats.

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Selective Na+/H+ exchange inhibition by cariporide reduces liver fibrosis in the rat.

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Inhibitory effect of soluble PDGF-beta receptor in culture-activated hepatic stellate cells.

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Dominant-negative soluble PDGF-beta receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis

21 January 2018

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Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis

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Therapeutic short hairpin RNA expression in the liver: viral targets and vectors

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Liver extracellular matrix in health and disease

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Effect of interleukin-10 and platelet-derived growth factor on expressions of matrix metalloproteinases-2 and tissue inhibitor of metalloproteinases-1 in rat fibrotic liver and cultured hepatic stellate cells

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Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis

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Connective tissue growth factor induces c-fos gene activation and cell proliferation through p44/42 MAP kinase in primary rat hepatic stellate cells

21 January 2018

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Cirrhotic rat livers with extensive fibrosis can be safely transduced with clinical-grade adenoviral vectors. Evidence of cirrhosis reversion

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Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis.

21 January 2018

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The role of platelet-derived growth factor signaling in healing myocardial infarcts.

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CSRP2, TIMP-1, and SM22alpha promoter fragments direct hepatic stellate cell-specific transgene expression in vitro, but not in vivo

21 January 2018

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Cell type-specific intervention of transforming growth factor beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice

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Extra-neural glial fibrillary acidic protein (GFAP) immunoreactivity in perisinusoidal stellate cells of rat liver.

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Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers

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GFAP promoter directs lacZ expression specifically in a rat hepatic stellate cell line

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A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

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An RNA polymerase II construct synthesizes short-hairpin RNA with a quantitative indicator and mediates highly efficient RNAi

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The role of alpha1beta1 integrin in wound contraction. A quantitative analysis of liver myofibroblasts in vivo and in primary culture

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Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

21 January 2018

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Single-step, multiple retroviral transduction of human T cells

21 January 2018

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Liver fibrosis induced by hepatic overexpression of PDGF-B in transgenic mice

21 January 2018

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7 January 2021

PDGF and signal transduction in hepatic stellate cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.93

7 January 2021

Extracellular signal-regulated kinase activation differentially regulates platelet-derived growth factor's actions in hepatic stellate cells, and is induced byIn Vivo liver injury in the rat

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.93

7 January 2021

Platelet-derived growth factor receptor tyrosine kinase inhibitor AG1295 attenuates rat hepatic stellate cell growth

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https://api.crossref.org/works/10.1038%2FGT.2008.93

7 January 2021

Platelet-derived growth factor (PDGF)-BB stimulates osteoclastic bone resorption directly: the role of receptor beta

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https://api.crossref.org/works/10.1038%2FGT.2008.93

7 January 2021

Control of the tissue inhibitor of metalloproteinases-1 promoter in culture-activated rat hepatic stellate cells: regulation by activator protein-1 DNA binding proteins

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https://api.crossref.org/works/10.1038%2FGT.2008.93

7 January 2021

The vimentin‐GFA protein transition in rat neuroglia cytoskeleton occurs at the time of myelination

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.93

7 January 2021

GFAP promoter directs astrocyte-specific expression in transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.93

7 January 2021

High-level expression of naked DNA delivered to rat liver via tail vein injection

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.93

7 January 2021

Efficient delivery of siRNA for inhibition of gene expression in postnatal mice

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.93

7 January 2021

Identifiers

DOI

10.1038/GT.2008.93

1 reference

Dimensions Publication ID

16 September 2017

1045107579

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