Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. (Q39962425)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14532116%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

title

Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein (English)

1 reference

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19 December 2019

main subject

prion protein family

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endoplasmic reticulum

0 references

1 reference

1 reference

4

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19 December 2019

author name string

Claudio Hetz

1

1 reference

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19 December 2019

Milene Russelakis-Carneiro

2

1 reference

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19 December 2019

Kinsey Maundrell

3

1 reference

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19 December 2019

Claudio Soto

5

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19 December 2019

language of work or name

English

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publication date

1 October 2003

1 reference

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19 December 2019

1 reference

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19 December 2019

volume

22

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19 December 2019

issue

20

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19 December 2019

page(s)

5435-5445

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Protein misfolding and disease: the case of prion disorders

19 December 2019

cites work

1 reference

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Overexpressed protein disulfide isomerase in brains of patients with sporadic Creutzfeldt-Jakob disease

22 September 2017

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Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase

22 September 2017

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Human caspase 12 has acquired deleterious mutations

22 September 2017

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Microcin E492, a channel-forming bacteriocin from Klebsiella pneumoniae, induces apoptosis in some human cell lines

22 September 2017

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Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding

22 September 2017

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22 September 2017

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Cultured cell sublines highly susceptible to prion infection

22 September 2017

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22 September 2017

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

22 September 2017

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Biochemical pathways of caspase activation during apoptosis

22 September 2017

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22 September 2017

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A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis.

22 September 2017

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Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins

22 September 2017

1 reference

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Transient expression of wild-type or mitochondrially targeted Bcl-2 induces apoptosis, whereas transient expression of endoplasmic reticulum-targeted Bcl-2 is protective against Bax-induced cell death

22 September 2017

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Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells

25 September 2017

1 reference

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Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation

25 September 2017

1 reference

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An endoplasmic reticulum-specific stress-activated caspase (caspase-12) is implicated in the apoptosis of A549 epithelial cells by respiratory syncytial virus

25 September 2017

1 reference

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Prion protein amyloidosis

25 September 2017

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Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells

25 September 2017

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Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway

25 September 2017

1 reference

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Caspases find a new place to hide.

15 June 2018

1 reference

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Erp61 is GRP58, a stress-inducible luminal endoplasmic reticulum protein, but is devoid of phosphatidylinositide-specific phospholipase C activity

15 June 2018

1 reference

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In vitro replication of scrapie agent in a neuronal model: infection of PC12 cells.

15 June 2018

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Stimulation of PrP(C) retrograde transport toward the endoplasmic reticulum increases accumulation of PrP(Sc) in prion-infected cells

15 June 2018

1 reference

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Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation

20 August 2018

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Wild-type, mitochondrial and ER-restricted Bcl-2 inhibit DNA damage-induced apoptosis but do not affect death receptor-induced apoptosis.

20 August 2018

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Neurotoxicity but not infectivity of prion proteins can be induced reversibly in vitro.

20 August 2018

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Neurotoxicity of a prion protein fragment.

20 August 2018

1 reference

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The Metabolism and Imaging in Live Cells of the Bovine Prion Protein in Its Native Form or Carrying Single Amino Acid Substitutions

20 August 2018

1 reference

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Prion Protein Aggregation Reverted by Low Temperature in Transfected Cells Carrying a Prion Protein Gene Mutation

2 December 2018

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12 December 2020

Cell Death in Development

1 reference

12 December 2020

Proteasomal Degradation and N-terminal Protease Resistance of the Codon 145 Mutant Prion Protein

1 reference

12 December 2020

Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides

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12 December 2020

The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the Proteasome

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12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDG537

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14532116%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14532116%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

1 reference