Active N-Ras and B-Raf inhibit anoikis by downregulating Bim expression in melanocytic cells. (Q39955638)

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11 January 2020

title

Active N-Ras and B-Raf inhibit anoikis by downregulating Bim expression in melanocytic cells (English)

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11 January 2020

7

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11 January 2020

author name string

Nathaniel B Goldstein

1

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11 January 2020

Widya U Johannes

2

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11 January 2020

Agnessa V Gadeliya

3

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11 January 2020

Matthew R Green

4

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11 January 2020

Mayumi Fujita

5

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11 January 2020

David A Norris

6

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11 January 2020

language of work or name

English

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publication date

31 July 2008

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Journal of Investigative Dermatology

11 January 2020

published in

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11 January 2020

volume

129

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11 January 2020

issue

2

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11 January 2020

page(s)

432-437

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https://scigraph.springernature.com/pub.10.1038/jid.2008.227

11 January 2020

exact match

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cites work

Mutant B-RAF mediates resistance to anoikis via Bad and Bim.

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7 January 2021

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G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression

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Bim expression is reduced in human cutaneous melanomas

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Mutations of the BRAF gene in human cancer

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Proapoptotic BH3-only BCL-2 family protein BIM connects death signaling from epidermal growth factor receptor inhibition to the mitochondrion

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Suppression of oncogenic NRAS by RNA interference induces apoptosis of human melanoma cells.

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Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity.

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A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death

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Generation of a human melanocyte cell line by introduction of HPV16 E6 and E7 genes

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Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

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EGFR-dependent downregulation of Bim in epithelial cells requires MAPK and PKC-delta activities

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7 January 2021

Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes.

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Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis

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7 January 2021

Anoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis

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7 January 2021