High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability. (Q39953729)

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English	High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability.	scientific article

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11 January 2020

High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability (English)

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11 January 2020

neoplastic stem cells

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inferred from title

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Alysha K Croker

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11 January 2020

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Alison L Allan

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11 January 2020

author name string

David Goodale

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Jenny Chu

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Carl Postenka

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Benjamin D Hedley

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David A Hess

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publication date

4 August 2008

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Journal of Cellular and Molecular Medicine

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13

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2236-2252

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8B

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describes a project that uses

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11 June 2022

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Dissemination and growth of cancer cells in metastatic sites

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Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases.

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

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Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity.

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Prospective identification of tumorigenic breast cancer cells

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Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

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Beyond tumorigenesis: cancer stem cells in metastasis

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Cancer stem cells: implications for the progression and treatment of metastatic disease.

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CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis

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Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype

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The prognostic role of a gene signature from tumorigenic breast-cancer cells.

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Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

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Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man?

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Breast cancer stem cells: a case of mistaken identity?

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Molecular definition of breast tumor heterogeneity

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Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity

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Retinoids run rampant: multiple roles during spinal cord and motor neuron development

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Widespread nonhematopoietic tissue distribution by transplanted human progenitor cells with high aldehyde dehydrogenase activity.

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Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity.

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Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells

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Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples

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ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

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Technical considerations for studying cancer metastasis in vivo

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MDA-MB-435 cells are derived from M14 melanoma cells--a loss for breast cancer, but a boon for melanoma research

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Common origins of MDA-MB-435 cells from various sources with those shown to have melanoma properties.

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Role of the integrin-binding protein osteopontin in lymphatic metastasis of breast cancer

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Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice

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let-7 regulates self renewal and tumorigenicity of breast cancer cells

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Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis

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Segregation of lipid raft markers including CD133 in polarized human hematopoietic stem and progenitor cells.

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Human aldehyde dehydrogenases: potential pathological, pharmacological, and toxicological impact

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1 reference

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Prevalence of CD44+/CD24-/low cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Metastatic Inefficiency

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood

1 reference

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Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential

1 reference

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1 reference

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1 reference

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Identifiers

10.1111/J.1582-4934.2008.00455.X

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11 January 2020

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11 January 2020

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11 January 2020

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