Increased alternative splicing of the KLF6 tumour suppressor gene correlates with prognosis and tumour grade in patients with pancreatic cancer. (Q39952141)

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English	Increased alternative splicing of the KLF6 tumour suppressor gene correlates with prognosis and tumour grade in patients with pancreatic cancer.	scientific article

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scholarly article

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12 January 2020

Increased alternative splicing of the KLF6 tumour suppressor gene correlates with prognosis and tumour grade in patients with pancreatic cancer (English)

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12 January 2020

0 references

alternative mRNA splicing, via spliceosome

1 reference

based on heuristic

inferred from title

2

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12 January 2020

7

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Helmut Friess

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12 January 2020

3

object named as

Moritz N Wente

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12 January 2020

author name string

Mark Hartel

1

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12 January 2020

Nathalia A Giese

4

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12 January 2020

Marc E Martignoni

5

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12 January 2020

John A Martignetti

6

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12 January 2020

Scott L Friedman

8

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12 January 2020

publication date

6 August 2008

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12 January 2020

European Journal of Cancer

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12 January 2020

44

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12 January 2020

13

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12 January 2020

1895-1903

1 reference

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12 January 2020

Mammalian Krüppel-like transcription factors: more than just a pretty finger

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activation of urokinase by the Krüppel-like factor Zf9/COPEB activates latent TGF-beta1 in vascular endothelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic progression and divergence in pancreatic carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The grade of pancreatic ductal carcinoma is an independent prognostic factor and is superior to the immunohistochemical assessment of proliferation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular analysis of microdissected tumors and preneoplastic intraductal lesions in pancreatic carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biology of the mammalian Krüppel-like family of transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Krüppel-like factors: three fingers in many pies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KLF6, a candidate tumor suppressor gene mutated in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p16 and p53 gene alterations and accumulations in the malignant evolution of intraductal papillary-mucinous tumors of the pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sp1- and Krüppel-like transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion, mutation, and loss of expression of KLF6 in human prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KLF6, a putative tumor suppressor gene, is mutated in astrocytic gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laser microdissection of small tissue samples--application to chronic pancreatitis tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of glioblastoma tumorigenicity by the Kruppel-like transcription factor KLF6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profiling predicts clinical outcome of prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Krüppel-like factor 6 is frequently down-regulated and induces apoptosis in non-small cell lung cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new role for the Krüppel-like transcription factor KLF6 as an inhibitor of c-Jun proto-oncoprotein function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent inactivation of the tumor suppressor Kruppel-like factor 6 (KLF6) in hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Germline DNA Polymorphism Enhances Alternative Splicing of theKLF6Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic alterations of the KLF6 gene in gastric cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic cancer: basic and clinical aspects

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment for pancreatic cancer: current therapy and continued progress

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular prognostic markers in pancreatic cancer: a systematic review

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conserved family of nuclear proteins containing structural elements of the finger protein encoded by Krüppel, a Drosophila segmentation gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel human zinc finger protein that interacts with the core promoter element of a TATA box-less gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zf9, a Kruppel-like transcription factor up-regulated in vivo during early hepatic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activation of transforming growth factor beta1 and its receptors by the Kruppel-like factor Zf9/core promoter-binding protein and Sp1. Potential mechanisms for autocrine fibrogenesis in response to injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18691883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EJCA.2008.06.030

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12 January 2020

1 reference

Europe PubMed Central

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12 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18691883%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

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