Functional dissection of the C-terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani (Q39922598)

https://doi.org/10.1093/nar/gkab317

15 September 2017

1 reference

29 December 2023

title

Functional dissection of the C-terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani (English)

1 reference

15 September 2017

Leishmania donovani

1 reference

Tanushri Sengupta

1

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15 September 2017

Mandira Mukherjee

2

1 reference

15 September 2017

Chhabinath Mandal

3

1 reference

15 September 2017

Aditi Das

4

1 reference

15 September 2017

Hemanta K Majumder

5

1 reference

15 September 2017

language of work or name

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1 September 2003

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15 September 2017

Nucleic Acids Research

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15 September 2017

31

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15 September 2017

18

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15 September 2017

5305-5316

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Protozomics: trypanosomatid parasite genetics comes of age.

15 September 2017

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Culprit and victim -- DNA topoisomerase II.

22 September 2017

1 reference

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Cellular roles of dna topoisomerases: a molecular perspective

22 September 2017

1 reference

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DNA topoisomerases: structure, function, and mechanism

22 September 2017

1 reference

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Characterisation of the gene encoding type II DNA topoisomerase from Leishmania donovani: a key molecular target in antileishmanial therapy

22 September 2017

1 reference

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Assignment of functional amino acids around the active site of human DNA topoisomerase IIalpha

22 September 2017

1 reference

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Using a biochemical approach to identify the primary dimerization regions in human DNA topoisomerase IIalpha

22 September 2017

1 reference

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Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

1 reference

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Structure and mechanism of DNA topoisomerase II

22 September 2017

1 reference

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22 September 2017

1 reference

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22 September 2017

1 reference

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22 September 2017

1 reference

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Preferential, cooperative binding of DNA topoisomerase II to scaffold-associated regions

22 September 2017

1 reference

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Biochemical basis for the interactions of type I and type II topoisomerases with DNA.

22 September 2017

1 reference

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The TOP2 gene of Trypanosoma brucei: a single-copy gene that shares extensive homology with other TOP2 genes encoding eukaryotic DNA topoisomerase II.

22 September 2017

1 reference

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Segregation of recombined chromosomes in meiosis I requires DNA topoisomerase II.

22 September 2017

1 reference

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Getting started with yeast

22 September 2017

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22 September 2017

1 reference

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One-step transformation of yeast in stationary phase

22 September 2017

1 reference

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Proteolysis patterns of epitopically labeled yeast DNA topoisomerase II suggest an allosteric transition in the enzyme induced by ATP binding

22 September 2017

1 reference

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Nuclear targeting sequences--a consensus?

22 September 2017

1 reference

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A functional 125-kDa core polypeptide of fission yeast DNA topoisomerase II

22 September 2017

1 reference

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Isolation of cDNA clones encoding the beta isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24

22 September 2017

1 reference

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Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation

22 September 2017

1 reference

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Cloning and characterization of the gene encoding Trypanosoma cruzi DNA topoisomerase II.

22 September 2017

1 reference

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Casein kinase II phosphorylates the eukaryote-specific C-terminal domain of topoisomerase II in vivo

22 September 2017

1 reference

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Molecular cloning and expression of the gene encoding the kinetoplast-associated type II DNA topoisomerase of Crithidia fasciculata

22 September 2017

1 reference

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T4 DNA topoisomerase: a new ATP-dependent enzyme essential for initiation of T4 bacteriophage DNA replication

22 September 2017

1 reference

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DNA gyrase: an enzyme that introduces superhelical turns into DNA

22 September 2017

1 reference

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DNA topoisomerase II mutations and resistance to anti-tumor drugs

22 September 2017

1 reference

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Appendix. II: Alignment of primary sequences of DNA topoisomerases.

25 September 2017

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Dihydrobetulinic acid induces apoptosis in Leishmania donovani by targeting DNA topoisomerase I and II: implications in antileishmanial therapy.

25 September 2017

1 reference

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A novel active DNA topoisomerase I in Leishmania donovani.

17 June 2018

1 reference

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Luteolin, an abundant dietary component is a potent anti-leishmanial agent that acts by inducing topoisomerase II-mediated kinetoplast DNA cleavage leading to apoptosis

17 June 2018

1 reference

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The C-terminal domain of Saccharomyces cerevisiae DNA topoisomerase II.

17 June 2018

1 reference

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17 June 2018

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Chromosome assembly in vitro: Topoisomerase II is required for condensation

17 June 2018

1 reference

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During both interphase and mitosis, DNA topoisomerase II interacts with DNA as well as RNA through the protein's C-terminal domain.

17 June 2018

1 reference

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Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine

20 August 2018

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Function of the hydrophilic carboxyl terminus of type II DNA topoisomerase from Drosophila melanogaster. II. In vivo studies.

20 August 2018

1 reference

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Linker insertion mutagenesis of Drosophila topoisomerase II. Probing the structure of eukaryotic topoisomerase II.

20 August 2018

1 reference

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Serine 1524 is a major site of phosphorylation on human topoisomerase II alpha protein in vivo and is a substrate for casein kinase II in vitro.

20 August 2018

1 reference

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Metaphase chromosome structure. Involvement of topoisomerase II

20 August 2018

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12 December 2020

Decatenation of kinetoplast DNA by an ATP-dependent DNA topoisomerase from the kinetoplast hemoflagellate Leishmania donovani

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12 December 2020

Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes

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12 December 2020

An ATP-independent catenating enzyme from the kinetoplast hemoflagellate Leishmania donovani

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12 December 2020

The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases

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Use of yeast in the study of anticancer drugs targeting DNA topoisomerases: expression of a functional recombinant human DNA topoisomerase II alpha in yeast

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Identifiers

DOI

10.1093/NAR/GKG727

1 reference

15 September 2017

1 reference

15 September 2017

PubMed publication ID

12954766

1 reference