Distinctive molecular signaling in triple-negative breast cancer cell death triggered by hexadecylphosphocholine (miltefosine). (Q39910888)

15 September 2017

Distinctive molecular signaling in triple-negative breast cancer cell death triggered by hexadecylphosphocholine (miltefosine). (English)

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triple-negative breast cancer

15 September 2017

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Krittalak Chakrabandhu

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1

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15 September 2017

Sébastien Huault

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2

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15 September 2017

Anne-Odile Hueber

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3

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15 September 2017

language of work or name

English

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publication date

28 November 2008

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15 September 2017

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15 September 2017

582

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15 September 2017

30

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15 September 2017

4176-4184

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Triple-negative breast cancer: clinical features and patterns of recurrence

15 September 2017

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.11.019

Loco-regional control of cutaneous metastases of malignant melanoma by treatment with miltefosine (Miltex).

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Treatment of cutaneous metastases of a squamous cell carcinoma of the leg with topical miltefosine

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Phase II study of daily oral miltefosine (hexadecylphosphocholine) in advanced colorectal cancer

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Miltefosine--discovery of the antileishmanial activity of phospholipid derivatives

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Palmitoylation is required for efficient Fas cell death signaling

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The extracellular glycosphingolipid-binding motif of Fas defines its internalization route, mode and outcome of signals upon activation by ligand.

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1 reference

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Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis

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Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: involvement of the Fas receptor/ligand system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.11.019

Relevance of breast cancer cell lines as models for breast tumours: an update

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.11.019

Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization

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MDA-MB-435 cells are derived from M14 melanoma cells--a loss for breast cancer, but a boon for melanoma research

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1 reference

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Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro

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1 reference

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Establishment and characterisation of a new tumorigenic cell line with a normal karyotype derived from a human breast adenocarcinoma

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BRCA1a has antitumor activity in TN breast, ovarian and prostate cancers.

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An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes

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Antineoplastic activity of alkylphosphocholines (APC) in human breast carcinomas in vivo and in vitro; use of liposomes.

21 January 2018

1 reference

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Characterization of two human mammary carcinomas, MT-1 and MT-3, suitable for in vivo testing of ether lipids and their derivatives

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Widespread intraspecies cross-contamination of human tumor cell lines arising at source.

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Hexadecylphosphocholine causes rapid cell death in canine mammary tumour cells

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Expression of different phenotypes in cell lines from canine mammary spindle-cell tumours and osteosarcomas indicating a pluripotent mammary stem cell origin.

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Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway

21 January 2018

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p38 MAPK in development and cancer

21 January 2018

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p38-MAPK signals survival by phosphorylation of caspase-8 and caspase-3 in human neutrophils

21 January 2018

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The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

21 January 2018

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Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells

21 January 2018

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Miltefosine to treat leishmaniasis

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.11.019

10.1016/J.FEBSLET.2008.11.019

21 January 2018

Identifiers

DOI

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15 September 2017

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