MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells. (Q39908262)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19059936%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells (English)

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18 January 2020

2

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18 January 2020

Matthew Jenner

3

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18 January 2020

Nicholas J Dickens

4

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18 January 2020

Gareth J Morgan

11

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18 January 2020

author name string

Jose L R Brito

1

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18 January 2020

Nicola J M Brown

5

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18 January 2020

Fiona M Ross

6

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18 January 2020

Athanasia Avramidou

7

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18 January 2020

Julie A E Irving

8

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18 January 2020

David Gonzalez

9

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18 January 2020

Faith E Davies

10

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18 January 2020

publication date

4 December 2008

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18 January 2020

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18 January 2020

volume

94

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18 January 2020

page(s)

78-86

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18 January 2020

issue

1

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Streptolysin-O reversible permeabilisation is an effective method to transfect siRNAs into myeloma cells.

18 January 2020

cites work

1 reference

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Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells

22 September 2017

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The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

22 September 2017

1 reference

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The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity.

22 September 2017

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Targeting the phosphatidylinositol 3-kinase pathway in multiple myeloma

22 September 2017

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22 September 2017

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22 September 2017

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ADAM-9 (MDC-9/meltrin-gamma), a member of the a disintegrin and metalloproteinase family, regulates myeloma-cell-induced interleukin-6 production in osteoblasts by direct interaction with the alpha(v)beta5 integrin

22 September 2017

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Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients

22 September 2017

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Phosphoinositide 3-kinase and Forkhead, a switch for cell division

22 September 2017

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Inhibition of fibroblast growth factor receptor 3 induces differentiation and apoptosis in t(4;14) myeloma.

22 September 2017

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22 September 2017

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A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript

22 September 2017

1 reference

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The enigma of ectopic expression of FGFR3 in multiple myeloma: a critical initiating event or just a target for mutational activation during tumor progression

22 September 2017

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Multiple myeloma: evolving genetic events and host interactions

22 September 2017

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MDC-9 (ADAM-9/Meltrin gamma) functions as an adhesion molecule by binding the alpha(v)beta(5) integrin

22 September 2017

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Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma

22 September 2017

1 reference

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Detection of t(4;14)(p16.3;q32) chromosomal translocation in multiple myeloma by reverse transcription-polymerase chain reaction analysis of IGH-MMSET fusion transcripts

22 September 2017

1 reference

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Role of INTERLEUKIN-6 in the pathogenesis of multiple myeloma

22 September 2017

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

22 September 2017

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The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts

22 September 2017

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A novel chromosomal translocation t(4; 14)(p16.3; q32) in multiple myeloma involves the fibroblast growth-factor receptor 3 gene

22 September 2017

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Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases

22 September 2017

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Deregulated FGFR3 mutants in multiple myeloma cell lines with t(4;14): comparative analysis of Y373C, K650E and the novel G384D mutations

22 September 2017

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Nuclear delivery of antisense oligodeoxynucleotides through reversible permeabilization of human leukemia cells with streptolysin O.

25 September 2017

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Suprabasal Dsg2 expression in transgenic mouse skin confers a hyperproliferative and apoptosis-resistant phenotype to keratinocytes

25 September 2017

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15 June 2018

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Correlation of TACC3, FGFR3, MMSET and p21 expression with the t(4;14)(p16.3;q32) in multiple myeloma.

20 August 2018

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A molecular study of the t(4;14) in multiple myeloma.

20 August 2018

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Signal transduction from N-cadherin increases Bcl-2. Regulation of the phosphatidylinositol 3-kinase/Akt pathway by homophilic adhesion and actin cytoskeletal organization

20 August 2018

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20 August 2018

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Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma

20 August 2018

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12 December 2020

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma

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12 December 2020

In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression

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12 December 2020

Interleukin-10 is a growth factor for human myeloma cells by induction of an oncostatin M autocrine loop

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12 December 2020

IgH translocations in multiple myeloma: a nearly universal event that rarely involves c-myc

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12 December 2020

Antisense morpholino oligonucleotide analog induces missplicing of C-myc mRNA

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12 December 2020

Ectopic expression of fibroblast growth factor receptor 3 promotes myeloma cell proliferation and prevents apoptosis

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12 December 2020

Identifiers

DOI

10.3324/HAEMATOL.13426

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19059936%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19059936%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference