The effects of alpha-secretase ADAM10 on the proteolysis of neuregulin-1. (Q39883356)

15 September 2017

The effects of alpha-secretase ADAM10 on the proteolysis of neuregulin-1. (English)

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15 September 2017

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Christian Freese

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15 September 2017

Alistair N Garratt

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2

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15 September 2017

Falk Fahrenholz

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15 September 2017

Kristina Endres

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15 September 2017

language of work or name

English

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publication date

11 February 2009

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15 September 2017

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15 September 2017

276

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15 September 2017

6

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15 September 2017

1568-1580

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Neuregulin and ErbB receptor signaling pathways in the nervous system

15 September 2017

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Neuregulins: versatile growth and differentiation factors in nervous system development and human disease

21 January 2018

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Neuregulins: functions, forms, and signaling strategies

21 January 2018

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Multiple novel transcription initiation sites for NRG1

21 January 2018

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ErbB2 pathways in heart and neural diseases

21 January 2018

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Essential roles of Her2/erbB2 in cardiac development and function

21 January 2018

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Neuregulin-1beta modulates in vivo entorhinal-hippocampal synaptic transmission in adult rats.

21 January 2018

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A cysteine-rich isoform of neuregulin controls the level of expression of neuronal nicotinic receptor channels during synaptogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Regulation of neuregulin signaling by PSD-95 interacting with ErbB4 at CNS synapses

21 January 2018

1 reference

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Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat Schwann cell precursors.

21 January 2018

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Peripheral glia: Schwann cells in motion

21 January 2018

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Neuregulin 1 growth factors regulate proliferation but not apoptosis of a CNS neuronal progenitor cell line

21 January 2018

1 reference

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Neuregulin-1 isoforms are differentially expressed in the intact and regenerating adult rat nervous system.

21 January 2018

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Neuregulin-1 (NRG-1) mRNA and protein in the adult human brain

21 January 2018

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Neuregulin-1 and erbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease

21 January 2018

1 reference

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The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses

21 January 2018

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Neuregulin-1beta induces neurite extension and arborization in cultured hippocampal neurons

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Neuregulin-1 reverses long-term potentiation at CA1 hippocampal synapses.

21 January 2018

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Neuregulin 1 and susceptibility to schizophrenia

21 January 2018

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Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia.

21 January 2018

1 reference

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Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia

21 January 2018

1 reference

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Neuregulin: an oligodendrocyte growth factor absent in active multiple sclerosis lesions

21 January 2018

1 reference

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Meltrin beta (ADAM19) mediates ectodomain shedding of Neuregulin beta1 in the Golgi apparatus: fluorescence correlation spectroscopic observation of the dynamics of ectodomain shedding in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Control of peripheral nerve myelination by the beta-secretase BACE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Neuregulin-1 enhances survival of human astrocytic glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Back signaling by the Nrg-1 intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Neuregulin isoforms in dorsal root ganglion neurons: effects of the cytoplasmic domain on localization and membrane shedding of Nrg-1 type I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Bace1 modulates myelination in the central and peripheral nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Roles of Meltrin beta /ADAM19 in the processing of neuregulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

The APP family of proteins: similarities and differences

21 January 2018

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Integrative proteomics: functional and molecular characterization of a particular glutamate-related neuregulin isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

21 January 2018

1 reference

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A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Over-expression of two different forms of the alpha-secretase ADAM10 affects learning and memory in mice.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

The amyloid pathology progresses in a neurotransmitter-specific manner

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Multiple essential functions of neuregulin in development

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Neu and its ligands: from an oncogene to neural factors

21 January 2018

1 reference

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Differential regulation of neuregulin 1 expression by progesterone in astrocytes and neurons

21 January 2018

1 reference

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ErbB-4 and neuregulin expression in the adult mouse olfactory bulb after peripheral denervation.

21 January 2018

1 reference

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Neuregulin-1alpha and beta isoform expression in cardiac microvascular endothelial cells and function in cardiac myocytes in vitro

21 January 2018

1 reference

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Studies on the structure and function of glycosylated and nonglycosylated neu differentiation factors. Similarities and differences of the alpha and beta isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Effects of neuron-specific ADAM10 modulation in an in vivo model of acute excitotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Axonal regulation of myelination by neuregulin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Cyclic AMP synergistically enhances neuregulin-dependent ERK and Akt activation and cell cycle progression in Schwann cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Neuregulin-1 proteins in rat brain and transfected cells are localized to lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Lipid rafts identified as locations of ectodomain shedding mediated by Meltrin beta/ADAM19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Characterization of transgene expression and Cre recombinase activity in a panel of Thy-1 promoter-Cre transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Hereditary hypertrophic neuropathy in the trembler mouse. Part 2. Histopathological studies: electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Axonal neuregulin-1 regulates myelin sheath thickness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06889.X

10.1111/J.1742-4658.2009.06889.X

21 January 2018

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DOI

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15 September 2017

1 reference