Human T-cell leukemia virus type 1 Tax protein transforms rat fibroblasts via two distinct pathways. (Q39879883)

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3 November 2019

title

Human T-cell leukemia virus type 1 Tax protein transforms rat fibroblasts via two distinct pathways (English)

1 reference

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3 November 2019

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Human T-lymphotropic virus 1

1 reference

1 reference

Matsumoto K

1

1 reference

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3 November 2019

Shibata H

2

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3 November 2019

Fujisawa JI

3

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3 November 2019

Inoue H

4

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3 November 2019

Hakura A

5

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3 November 2019

Tsukahara T

6

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3 November 2019

Fujii M

7

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3 November 2019

language of work or name

English

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publication date

1 June 1997

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3 November 2019

number of pages

7

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based on heuristic

inferred from page(s)

published in

Journal of Virology

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3 November 2019

volume

71

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3 November 2019

page(s)

4445-4451

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3 November 2019

issue

6

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Constitutive activation of NF-kappa B is essential for transformation of rat fibroblasts by the human T-cell leukemia virus type I Tax protein

3 November 2019

cites work

1 reference

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HTLV-1 Tax protein interacts with cyclin-dependent kinase inhibitor p16INK4A and counteracts its inhibitory activity towards CDK4.

22 September 2017

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Proliferative response of Tax1-transduced primary human T cells to anti-CD3 antibody stimulation by an interleukin-2-independent pathway.

22 September 2017

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The trans-activator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1.

22 September 2017

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A trans-activator Tax of human T-cell leukemia virus type 1 binds to NF-kappa B p50 and serum response factor (SRF) and associates with enhancer DNAs of the NF-kappa B site and CArG box.

22 September 2017

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Human T-cell leukemia virus type 1 Tax activates transcription of the human fra-1 gene through multiple cis elements responsive to transmembrane signals

22 September 2017

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Transcriptional regulation of the human interleukin-6 gene promoter in human T-cell leukemia virus type I-infected T-cell lines: evidence for the involvement of NF-kappa B.

22 September 2017

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Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

22 September 2017

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Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I.

22 September 2017

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Identification of p40x-responsive regulatory sequences within the human T-cell leukemia virus type I long terminal repeat

22 September 2017

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Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1.

22 September 2017

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Requirement of multiple copies of a 21-nucleotide sequence in the U3 regions of human T-cell leukemia virus type I and type II long terminal repeats for trans-acting activation of transcription

22 September 2017

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Functional activation of the long terminal repeat of human T-cell leukemia virus type I by a trans-acting factor

22 September 2017

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c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I

22 September 2017

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HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene

22 September 2017

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SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

22 September 2017

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Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat

22 September 2017

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A human beta-actin expression vector system directs high-level accumulation of antisense transcripts

22 September 2017

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The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells

22 September 2017

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Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia

22 September 2017

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22 September 2017

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22 September 2017

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Molecular cloning and characterization of a novel glycoprotein, gp34, that is specifically induced by the human T-cell leukemia virus type I transactivator p40tax

22 September 2017

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Type I human T cell leukemia virus tax protein transforms rat fibroblasts through the cyclic adenosine monophosphate response element binding protein/activating transcription factor pathway

22 September 2017

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Four regulatory elements in the human c-fos promoter mediate transactivation by HTLV-1 Tax protein

22 September 2017

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HTLV-1 Tax has distinct but overlapping domains for transcriptional activation and for enhancer specificity.

22 September 2017

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Transactivation of the c-myc promoter by human T cell leukemia virus type 1 tax is mediated by NF kappa B.

22 September 2017

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Transcriptional activator Tax of HTLV-1 binds to the NF-kappa B precursor p105

22 September 2017

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Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes

22 September 2017

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Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction

22 September 2017

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Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture

22 September 2017

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Transactivation of the human interleukin-6 gene by human T-lymphotropic virus type 1 Tax protein.

22 September 2017

1 reference

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Tax protein of HTLV-1 interacts with the Rel homology domain of NF-kappa B p65 and c-Rel proteins bound to the NF-kappa B binding site and activates transcription.

25 September 2017

1 reference

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Tax protein of HTLV-1 destabilizes the complexes of NF-kappa B and I kappa B-alpha and induces nuclear translocation of NF-kappa B for transcriptional activation

25 September 2017

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HTLV-I encoded Tax in association with NF-kappa B precursor p105 enhances nuclear localization of NF-kappa B p50 and p65 in transfected cells.

25 September 2017

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Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency

17 June 2018

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Regulation of the human interleukin-2 receptor alpha chain promoter: activation of a nonfunctional promoter by the transactivator gene of HTLV-I.

17 June 2018

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A transcriptional enhancer sequence of HTLV-I is responsible for trans-activation mediated by p40 chi HTLV-I.

17 June 2018

1 reference

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The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice

17 June 2018

1 reference

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Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes

17 June 2018

1 reference

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Transactivation of Krox-20 and Krox-24 promoters by the HTLV-1 Tax protein through common regulatory elements.

17 June 2018

1 reference

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Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator protein

17 June 2018

1 reference

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HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-kappa B-like factor.

17 June 2018

1 reference

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Evidence in support of a role for human T-cell leukemia virus type I Tax in activating NF-kappa B via stimulation of signaling pathways

3 July 2018

1 reference

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HTLV-1 oncoprotein Tax deregulates transcription of cellular genes through multiple mechanisms.

20 August 2018

1 reference

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Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191663

HTLV-1 Tax induces expression of various immediate early serum responsive genes

20 August 2018

1 reference

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Single amino acid substitution (58Pro-->Ser) in HTLV-I tax results in loss of ras cooperative focus formation in rat embryo fibroblasts

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9151835

inferred from PubMed ID database lookup

12 December 2020

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Identifiers

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3 November 2019

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