Activation of the human thymidine kinase (TK) promoter by simian virus 40 large T antigen requires both the T antigen pRb family-binding domain and TK promoter sequences resembling E2F-binding sites. (Q39876169)

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scientific article published on September 1996

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English	Activation of the human thymidine kinase (TK) promoter by simian virus 40 large T antigen requires both the T antigen pRb family-binding domain and TK promoter sequences resembling E2F-binding sites.	scientific article published on September 1996

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scholarly article

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17 October 2019

Activation of the human thymidine kinase (TK) promoter by simian virus 40 large T antigen requires both the T antigen pRb family-binding domain and TK promoter sequences resembling E2F-binding sites (English)

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17 October 2019

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simian virus 40

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M M Anderson

1

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17 October 2019

J Chen

2

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17 October 2019

C N Cole

3

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17 October 2019

S E Conrad

4

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1 September 1996

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17 October 2019

Journal of Virology

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17 October 2019

70

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17 October 2019

9

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17 October 2019

6304-6313

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17 October 2019

Interaction between T antigen and TEA domain of the factor TEF-1 derepresses simian virus 40 late promoter in vitro: identification of T-antigen domains important for transcription control

1 reference

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The major transcriptional transactivation domain of simian virus 40 large T antigen associates nonconcurrently with multiple components of the transcriptional preinitiation complex

1 reference

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Temporal regulation of cyclin A-p107 and p33cdk2 complexes binding to a human thymidine kinase promoter element important for G1-S phase transcriptional regulation

1 reference

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A binding site for transcription factor E2F is a target for trans activation of murine thymidine kinase by polyomavirus large T antigen and plays an important role in growth regulation of the gene.

1 reference

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1 reference

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Transcriptional activation by simian virus 40 large T antigen: interactions with multiple components of the transcription complex

1 reference

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Transcriptional activation by simian virus 40 large T antigen: requirements for simple promoter structures containing either TATA or initiator elements with variable upstream factor binding sites

1 reference

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Regulation of the cellular thymidine kinase gene promoter in simian virus 40-infected cells

1 reference

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Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1 reference

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E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product

1 reference

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The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.

1 reference

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22 September 2017

Analysis of p107-associated proteins: p107 associates with a form of E2F that differs from pRB-associated E2F-1

1 reference

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22 September 2017

E2F-4, a new member of the E2F transcription factor family, interacts with p107

1 reference

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E2F-5, a new E2F family member that interacts with p130 in vivo

1 reference

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Sequence-specific binding of simian virus 40 A protein to nonorigin and cellular DNA

1 reference

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22 September 2017

Monoclonal antibodies specific for simian virus 40 tumor antigens

1 reference

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Hygromycin B Phosphotransferase as a Selectable Marker for DNA Transfer Experiments with Higher Eucaryotic Cells

1 reference

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22 September 2017

Simian virus 40 T antigen binds to DNA

1 reference

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22 September 2017

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

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22 September 2017

Regulation of c-myc and c-fos mRNA levels by polyomavirus: distinct roles for the capsid protein VP1 and the viral early proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190656

22 September 2017

Induction of cellular thymidine kinase occurs at the mRNA level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190656

22 September 2017

Transient gene expression control: effects of transfected DNA stability and trans-activation by viral early proteins

1 reference

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22 September 2017

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190656

22 September 2017

Properties of the DNA-binding domain of the simian virus 40 large T antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190656

22 September 2017

Linker insertion mutants of simian virus 40 large T antigen that show trans-dominant interference with wild-type large T antigen map to multiple sites within the T-antigen gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190656

22 September 2017

Identification of a G1-S-phase-regulated region in the human thymidine kinase gene promoter

1 reference

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Identification of a 70-base-pair cell cycle regulatory unit within the promoter of the human thymidine kinase gene and its interaction with cellular factors

1 reference

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Mapping the transcriptional transactivation function of simian virus 40 large T antigen

1 reference

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The E2F transcription factor is a cellular target for the RB protein

1 reference

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The ability of simian virus 40 large T antigen to immortalize primary mouse embryo fibroblasts cosegregates with its ability to bind to p53.

1 reference

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Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190656

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Identification of a protein-binding site in the promoter of the human thymidine kinase gene required for the G1-S-regulated transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190656

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1 reference

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Transformation of a continuous rat embryo fibroblast cell line requires three separate domains of simian virus 40 large T antigen

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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based on heuristic

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Activation of the SV40 late promoter: direct effects of T antigen in the absence of viral DNA replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/8709258

12 December 2020

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inferred from PubMed ID database lookup

In vitro mutagenesis of a putative DNA binding domain of SV40 large-T

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8709258%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8709258%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

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