Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase. (Q39844637)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483728%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase (English)

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29 January 2020

5

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29 January 2020

Richard B Lock

7

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29 January 2020

Roger Reddel

8

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29 January 2020

Karen MacKenzie

9

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6

V Rotter

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29 January 2020

author name string

J Yuan

1

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29 January 2020

B M-P Yang

2

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29 January 2020

Z-H Zhong

3

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29 January 2020

I Shats

4

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29 January 2020

language of work or name

English

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publication date

1 June 2009

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29 January 2020

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29 January 2020

volume

28

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29 January 2020

page(s)

2678-2689

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29 January 2020

issue

29

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https://scigraph.springernature.com/pub.10.1038/onc.2009.136

29 January 2020

exact match

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cites work

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

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Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex

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Extension of life-span by introduction of telomerase into normal human cells

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Survivin is required for stable checkpoint activation in taxol-treated HeLa cells

21 January 2018

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Protein composition of catalytically active human telomerase from immortal cells

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The hTERTalpha splice variant is a dominant negative inhibitor of telomerase activity

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Separating the anti-apoptotic and mitotic roles of survivin

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An IAP-IAP complex inhibits apoptosis

21 January 2018

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Regulation of the inhibitor-of-apoptosis family member survivin in normal cord blood and bone marrow CD34(+) cells by hematopoietic growth factors: implication of survivin expression in normal hematopoiesis

21 January 2018

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Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis

21 January 2018

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Differential requirements for survivin in hematopoietic cell development

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Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

21 January 2018

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Aberrant regulation of survivin by the RB/E2F family of proteins

21 January 2018

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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

21 January 2018

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The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function

21 January 2018

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Nuclear export is essential for the tumor-promoting activity of survivin.

21 January 2018

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Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension

21 January 2018

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Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

21 January 2018

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Control of apoptosis and mitotic spindle checkpoint by survivin

21 January 2018

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Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation.

21 January 2018

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Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-ras.

21 January 2018

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The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.

21 January 2018

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Cancer gene therapy using a survivin mutant adenovirus

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Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect.

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Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

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Targeting survivin in cancer therapy: fulfilled promises and open questions

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Survivin repression by p53, Rb and E2F2 in normal human melanocytes

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The role of senescence and immortalization in carcinogenesis

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Survivin as a radioresistance factor, and prognostic and therapeutic target for radiotherapy in rectal cancer.

21 January 2018

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Telomeres: cancer to human aging

21 January 2018

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Inactivation of p16INK4a, with retention of pRB and p53/p21cip1 function, in human MRC5 fibroblasts that overcome a telomere-independent crisis during immortalization.

21 January 2018

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Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype

21 January 2018

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Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs

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Transforming growth factor beta induces apoptosis through repressing the phosphoinositide 3-kinase/AKT/survivin pathway in colon cancer cells.

21 January 2018

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Disruption of the inhibitor of apoptosis protein survivin sensitizes Bcr-abl-positive cells to STI571-induced apoptosis

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Telomerase activity in human germline and embryonic tissues and cells.

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Cell division and cell survival in the absence of survivin

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Rb/E2F4 and Smad2/3 link survivin to TGF-beta-induced apoptosis and tumor progression

21 January 2018

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Telomere length of cord blood-derived CD34(+) progenitors predicts erythroid proliferative potential

21 January 2018

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