Development of quantitative structure-pharmacokinetic relationships (Q39834959)

15 September 2017

1 reference

6 August 2019

Development of quantitative structure-pharmacokinetic relationships (English)

1 reference

pharmaceutical preparation

15 September 2017

1 reference

6 August 2019

1 reference

J M Mayer

1

1 reference

PMCID

1568751

15 September 2017

H van de Waterbeemd

series ordinal

2

1 reference

15 September 2017

1 September 1985

2 references

Environmental Health Perspectives

15 September 2017

6 August 2019

2 references

15 September 2017

6 August 2019

61

1 reference

15 September 2017

295-306

1 reference

Prediction of the volume of distribution from in vitro data and use for estimating the absolute extent of absorption.

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Measurement of the renal clearance of drugs

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Influence of blood flow on intestinal absorption of xenobiotics

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Physiologically Based Pharmacokinetic Modeling: Principles and Applications

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Quantitative structure-pharmacokinetic relationships and drug design

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Influence of route of administration on drug availability

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Clearance concepts in pharmacokinetics

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Physicochemical-activity relations in practice. 1. Rational and self-consistent data bank

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Selection of a Reference Partitioning System for Drug Design Work

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Drugs, diseases and altered gastric emptying

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Lipophilicity and drug activity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Binding of Drugs by Albumin Plasma Protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Intestinal absorption-partition relationships: A tentative functional nonlinear model

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Symbols in pharmacokinetics.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Commentary: a physiological approach to hepatic drug clearance

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Antitumor 1-(X-aryl)-3,3-dialkyltriazenes. 2. On the role of correlation analysis in decision making in drug modification. Toxicity quantitative structure-activity relationships of 1-(X-phenyl)-3,3-dialkyltriazenes in mice

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Nitrosamine carcinogenicity: A quantitative Hansch-Taft structure-activity relationship

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

A pharmacokinetic model to differentiate preabsorptive, gut epithelial, and hepatic first-pass metabolism

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Effect of Altered Plasma Protein Binding on Apparent Volume of Distribution

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Quantitative Structure–Selectivity Relationships: Selective Drug Design

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Application of quantitative structure-activity relationships in the development of the antiallergic pyranenamines

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Metabolic structure-activity relationship for a homologous series of phenacetin analogs

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Quantitative structure-activity relationships in drug metabolism and disposition: pharmacokinetics of N-substituted amphetamines in humans.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Assessment of rate and extent of drug absorption

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Simultaneous pharmacokinetic and pharmacodynamic modeling

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Toxicity and quantitative structure-activity relationships of colchicines

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Carcinogenesis: a predictive structure-activity model.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Potential antitumor agents. 36. Quantitative relationships between experimental antitumor activity, toxicity, and structure for the general class of 9-anilinoacridine antitumor agents.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Structure-pharmacokinetic relationships among the barbiturates in the rat.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568751

Further characterization of specific drug binding sites on human serum albumin

20 August 2018

1 reference

12 December 2020

Relationship between partition coefficients and apparent volumes of distribution for basic drugs. II

1 reference

12 December 2020

Kinetic Analysis of Relationship between Partition Coefficient and Biological Response

1 reference

12 December 2020

Drug Metabolism by the Gastrointestinal Mucosa

1 reference

12 December 2020

Structure-pharmacokinetic relationships for misonidazole analogues in mice

1 reference

12 December 2020

Effect of polymorphism on the absorption of chloramphenicol from chloramphenicol palmitate

1 reference

12 December 2020

Hydrophobic binding of drugs to human albumin and ribonucleic acids

1 reference

12 December 2020

Drug absorption. I. An in situ rat gut technique yielding realistic absorption rates

1 reference

12 December 2020

Drug Absorption III: Effect of Membrane Storage on the Kinetics of Drug Absorption

1 reference

12 December 2020

Chromatographic hydrophobic parameters in correlation analysis of structure-activity relationships

1 reference

12 December 2020

Metabolism, pharmacokinetics, and toxicokinetics defined

1 reference

12 December 2020

The relationship between chemical structure and the in vivo metabolism of an homologous series of n-alkyl carbamates

1 reference

12 December 2020

Structure-toxicity relationships of selected nitrogenous heterocyclic compounds II. Dinitrogen molecules

1 reference

12 December 2020

Intestinal absorption of amino acid derivatives: structural requirements for membrane hydrolysis

1 reference

12 December 2020

Role of substrate lipophilicity on the N-demethylation and type I binding of 3-O-alkylmorphine analogues

1 reference

12 December 2020

Identifiers

DOI

10.1289/EHP.8561295

1 reference

15 September 2017

1 reference

15 September 2017

1 reference

PMCID

1568751