Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage. (Q39818706)

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English	Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage.	scientific article

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3 February 2020

Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage (English)

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3 February 2020

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3 February 2020

Gisela Taucher-Scholz

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Gisela Taucher-Scholz

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3 February 2020

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Martin F Lavin

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3 February 2020

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Janelle L Harris

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3 February 2020

Grigory L Dianov

4

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3 February 2020

Olivier J Becherel

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30 July 2009

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3 February 2020

Human Molecular Genetics

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3 February 2020

4102-4117

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21

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3 February 2020

Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Early-onset ataxia with ocular motor apraxia and hypoalbuminemia: the aprataxin gene mutations

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Phenotypic variability of aprataxin gene mutations

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Aprataxin gene mutations in Tunisian families

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Aprataxin mutations are a rare cause of early onset ataxia in Germany

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Short half-lives of ataxia-associated aprataxin proteins in neuronal cells.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Aprataxin, a novel protein that protects against genotoxic stress

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

DNA single-strand break repair is impaired in aprataxin-related ataxia.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

The FHA domain of aprataxin interacts with the C-terminal region of XRCC1

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

XRCC1 co-localizes and physically interacts with PCNA

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Defective DNA ligation during short-patch single-strand break repair in ataxia oculomotor apraxia 1

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Actions of aprataxin in multiple DNA repair pathways

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Reactions of oxyl radicals with DNA.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

DNA repair in mammalian cells: Base excision repair: the long and short of it.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

The PARP superfamily

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Base excision repair is impaired in mammalian cells lacking Poly(ADP-ribose) polymerase-1.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Poly(ADP-ribose) polymerase-1 (PARP-1) is required in murine cell lines for base excision repair of oxidative DNA damage in the absence of DNA polymerase beta

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

DNA repair defect in poly(ADP-ribose) polymerase-deficient cell lines

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Domain specific interaction in the XRCC1-DNA polymerase beta complex

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

APE1 is the major 3'-phosphoglycolate activity in human cell extracts

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

APE1-dependent repair of DNA single-strand breaks containing 3'-end 8-oxoguanine

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Mechanism of stimulation of the DNA glycosylase activity of hOGG1 by the major human AP endonuclease: bypass of the AP lyase activity step

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Functional sites of interaction between release factor RF1 and the ribosome

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

MRE11 mutations and impaired ATM-dependent responses in an Italian family with ataxia-telangiectasia-like disorder

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Live cell imaging of heavy-ion-induced radiation responses by beamline microscopy.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Biological imaging of heavy charged-particle tracks.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Recessive ataxia with ocular apraxia: review of 22 Portuguese patients

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Oxidative stress in neurodegeneration and available means of protection.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

A subgroup of spinocerebellar ataxias defective in DNA damage responses

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

The novel human gene aprataxin is directly involved in DNA single-strand-break repair.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Aprataxin forms a discrete branch in the HIT (histidine triad) superfamily of proteins with both DNA/RNA binding and nucleotide hydrolase activities

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Nucleolar localization of aprataxin is dependent on interaction with nucleolin and on active ribosomal DNA transcription

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

(ADP-ribose)n participates in DNA excision repair

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP359

21 January 2018

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