Site-specific N-glycosylation regulates the GPS auto-proteolysis of CD97. (Q39802247)

14 September 2017

Site-specific N-glycosylation regulates the GPS auto-proteolysis of CD97. (English)

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14 September 2017

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Cheng-Chih Hsiao

1

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14 September 2017

Kai-Fong Cheng

2

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14 September 2017

Hsin-Yi Chen

3

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14 September 2017

Yi-Hua Chou

4

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14 September 2017

Martin Stacey

5

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14 September 2017

Gin-Wen Chang

6

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14 September 2017

Hsi-Hsien Lin

7

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14 September 2017

language of work or name

English

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publication date

6 September 2009

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14 September 2017

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14 September 2017

583

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14 September 2017

3285-3290

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14 September 2017

19

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Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin

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Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif

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Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif

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Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site [...]

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Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.

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Improved antibacterial host defense and altered peripheral granulocyte homeostasis in mice lacking the adhesion class G protein receptor CD97.

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CD97, but not its closely related EGF-TM7 family member EMR2, is expressed on gastric, pancreatic, and esophageal carcinomas

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Individual cell-based models of tumor-environment interactions: Multiple effects of CD97 on tumor invasion

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CD97, an adhesion receptor on inflammatory cells, stimulates angiogenesis through binding integrin counterreceptors on endothelial cells

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The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans

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CD312, the human adhesion-GPCR EMR2, is differentially expressed during differentiation, maturation, and activation of myeloid cells.

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EMR4, a novel epidermal growth factor (EGF)-TM7 molecule up-regulated in activated mouse macrophages, binds to a putative cellular ligand on B lymphoma cell line A20

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Human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 is a new member of the EGF-TM7 family that recognizes a ligand on human macrophages and activated neutrophils

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Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G alpha 12/13 and Rho pathway.

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Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled

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Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure.

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1 reference

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Characterization of cis-autoproteolysis of polycystin-1, the product of human polycystic kidney disease 1 gene.

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Controlling N-linked glycan site occupancy

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10.1016/J.FEBSLET.2009.09.001

21 January 2018

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DOI

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14 September 2017

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