AIRE activated tissue specific genes have histone modifications associated with inactive chromatin (Q39801026)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19744957%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

AIRE activated tissue specific genes have histone modifications associated with inactive chromatin (English)

1 reference

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7 February 2020

3

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7 February 2020

Pärt Peterson

7

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7 February 2020

Tõnis Org

1

1 reference

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7 February 2020

Ana Rebane

2

1 reference

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7 February 2020

Uku Haljasorg

5

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7 February 2020

Reidar Andreson

6

1 reference

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7 February 2020

author name string

Martti Laan

4

1 reference

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7 February 2020

language of work or name

1 reference

10 September 2009

1 reference

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7 February 2020

published in

Human Molecular Genetics

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7 February 2020

volume

18

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7 February 2020

issue

24

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7 February 2020

page(s)

4699-4710

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19744957%20AND%20SRC:MED&resulttype=core&format=json

Clinical manifestations and management of patients with autoimmune polyendocrine syndrome type I.

7 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Transcriptional regulation by AIRE: molecular mechanisms of central tolerance

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Transcriptional impact of Aire varies with cell type

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Deletional tolerance mediated by extrathymic Aire-expressing cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

TiGER: a database for tissue-specific gene expression and regulation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Chromatin modifications and their function

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Spontaneous autoimmunity prevented by thymic expression of a single self-antigen

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

REEF: searching REgionally Enriched Features in genomes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

SP100B, a repressor of gene expression preferentially binds to DNA with unmethylated CpGs.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Cooperative activation of transcription by autoimmune regulator AIRE and CBP.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Chromosomal clustering of genes controlled by the aire transcription factor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Negative selection--clearing out the bad apples from the T-cell repertoire

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Aire regulates negative selection of organ-specific T cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Projection of an immunological self shadow within the thymus by the aire protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Aire deficient mice develop multiple features of APECED phenotype and show altered immune response

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

The autoimmune regulator (AIRE) is a DNA-binding protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Mutations in the AIRE gene: effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Medullary but not cortical thymic epithelial cells present soluble antigens to helper T cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

A quick and quantitative chromatin immunoprecipitation assay for small cell samples.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Highly variable expression of tissue-restricted self-antigens in human thymus: implications for self-tolerance and autoimmunity.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778368

Mapping DNA-binding domains of the autoimmune regulator protein

2 December 2018

1 reference

12 December 2020

Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice

1 reference

12 December 2020

CEAS: cis-regulatory element annotation system

1 reference

12 December 2020

The autoimmune regulator directly controls the expression of genes critical for thymic epithelial function

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDP433

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19744957%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19744957%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference