Inhibition of KSHV-infected primary effusion lymphomas in NOD/SCID mice by gamma-secretase inhibitor. (Q39794624)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19783901%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Inhibition of KSHV-infected primary effusion lymphomas in NOD/SCID mice by gamma-secretase inhibitor (English)

1 reference

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8 February 2020

5

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8 February 2020

8

Erle S Robertson

1 reference

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8 February 2020

author name string

Ke Lan

1

1 reference

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8 February 2020

Masanao Murakami

2

1 reference

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8 February 2020

Bharat Bajaj

3

1 reference

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8 February 2020

Rajeev Kaul

4

1 reference

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8 February 2020

Runliang Gan

6

1 reference

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8 February 2020

Michael Feldman

7

1 reference

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8 February 2020

publication date

7 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19783901%20AND%20SRC:MED&resulttype=core&format=json

Cancer Biology and Therapy

8 February 2020

published in

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8 February 2020

volume

8

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8 February 2020

page(s)

2136-2143

1 reference

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8 February 2020

issue

22

1 reference

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Inhibition of gamma-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells

8 February 2020

cites work

1 reference

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In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.

10 July 2018

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Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy

10 July 2018

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Liposomal daunorubicin as treatment for Kaposi's sarcoma

10 July 2018

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Kaposi's sarcoma herpesvirus-encoded latency-associated nuclear antigen stabilizes intracellular activated Notch by targeting the Sel10 protein

10 July 2018

1 reference

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Epstein-Barr virus latent nuclear antigens can induce metastasis in a nude mouse model

10 July 2018

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Notch inhibition in Kaposi's sarcoma tumor cells leads to mitotic catastrophe through nuclear factor-kappaB signaling.

10 July 2018

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Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus lymphomas: implications for therapy.

10 July 2018

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Structure and function of latency-associated nuclear antigen

10 July 2018

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Intracellular activated Notch1 is critical for proliferation of Kaposi's sarcoma-associated herpesvirus-associated B-lymphoma cell lines in vitro

10 July 2018

1 reference

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Transcriptional analysis of latent and inducible Kaposi's sarcoma-associated herpesvirus transcripts in the K4 to K7 region

10 July 2018

1 reference

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Induction of Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen by the lytic transactivator RTA: a novel mechanism for establishment of latency

10 July 2018

1 reference

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The role of Notch in tumorigenesis: oncogene or tumour suppressor?

10 July 2018

1 reference

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The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus manipulates the activity of glycogen synthase kinase-3beta

10 July 2018

1 reference

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A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency.

10 July 2018

1 reference

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The Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen binds to specific sequences at the left end of the viral genome through its carboxy-terminus

10 July 2018

1 reference

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The latency-associated nuclear antigen encoded by Kaposi's sarcoma-associated herpesvirus activates two major essential Epstein-Barr virus latent promoters

10 July 2018

1 reference

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Latency-associated nuclear antigen encoded by Kaposi's sarcoma-associated herpesvirus interacts with Tat and activates the long terminal repeat of human immunodeficiency virus type 1 in human cells

10 July 2018

1 reference

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The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus transactivates the telomerase reverse transcriptase promoter

10 July 2018

1 reference

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Epidemiology and pathogenesis of Kaposi's sarcoma-associated herpesvirus

10 July 2018

1 reference

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Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 mediates episome persistence through cis-acting terminal repeat (TR) sequence and specifically binds TR DNA.

10 July 2018

1 reference

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Modulation of cellular and viral gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus

10 July 2018

1 reference

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The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells

10 July 2018

1 reference

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Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling

10 July 2018

1 reference

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p53 inhibition by the LANA protein of KSHV protects against cell death

10 July 2018

1 reference

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Notch signaling: cell fate control and signal integration in development

10 July 2018

1 reference

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Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen

10 July 2018

1 reference

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LIN-12/Notch signaling: lessons from worms and flies

10 July 2018

1 reference

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Limited transmission of Kaposi's sarcoma-associated herpesvirus in cultured cells

10 July 2018

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Etiology of AIDS-related Kaposi's sarcoma and lymphoma

10 July 2018

1 reference

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The KSHV/HHV8-infected BCBL-1 lymphoma line causes tumors in SCID mice but fails to transmit virus to a human peripheral blood mononuclear cell graft

10 July 2018

1 reference

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Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)

10 July 2018

1 reference

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Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture

10 July 2018

1 reference

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Primary Characterization of a Herpesvirus Agent Associated with Kaposi’s Sarcoma

10 July 2018

1 reference

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Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

10 July 2018

1 reference

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Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5965683

In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposi's sarcoma-associated herpesvirus-like (KSHV) DNA sequences.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5965683

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5965683

Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5965683

Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5965683

Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5965683

Kaposi virus scores cancer coup

20 August 2018

1 reference

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Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19783901

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CBT.8.22.9743

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19783901%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19783901%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference