Identification of mutations in a candidate dengue 4 vaccine strain 341750 PDK20 and construction of a full-length cDNA clone of the PDK20 vaccine candidate (Q39781949)

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scientific article published on 27 October 2009

Language	Label	Description	Also known as
English	Identification of mutations in a candidate dengue 4 vaccine strain 341750 PDK20 and construction of a full-length cDNA clone of the PDK20 vaccine candidate	scientific article published on 27 October 2009

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scholarly article

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Europe PubMed Central

14 September 2017

Identification of mutations in a candidate dengue 4 vaccine strain 341750 PDK20 and construction of a full-length cDNA clone of the PDK20 vaccine candidate (English)

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Europe PubMed Central

14 September 2017

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author name string

Eileen P Kelly

1

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Europe PubMed Central

14 September 2017

Beena Puri

2

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Europe PubMed Central

14 September 2017

Wellington Sun

3

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Europe PubMed Central

14 September 2017

Barry Falgout

4

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Europe PubMed Central

14 September 2017

language of work or name

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publication date

27 October 2009

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Europe PubMed Central

14 September 2017

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Europe PubMed Central

14 September 2017

28

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Europe PubMed Central

14 September 2017

17

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Europe PubMed Central

14 September 2017

3030-3037

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Europe PubMed Central

14 September 2017

Dengue and dengue hemorrhagic fever

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Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity

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Differing influences of virus burden and immune activation on disease severity in secondary dengue-3 virus infections

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T cell responses in dengue hemorrhagic fever: are cross-reactive T cells suboptimal?

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Flavivirus genome organization, expression, and replication

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Preparation of an attenuated dengue 4 (341750 Carib) virus vaccine. II. Safety and immunogenicity in humans.

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Modification of dengue virus strains by passage in primary dog kidney cells: preparation of candidate vaccines and immunization of monkeys.

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The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution

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A ligand-binding pocket in the dengue virus envelope glycoprotein

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Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein

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Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformation

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Structure of the dengue virus envelope protein after membrane fusion

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Conformational changes of the flavivirus E glycoprotein

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High fidelity of yellow fever virus RNA polymerase

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Molecular basis for adaptation of a chimeric dengue type-4/Japanese encephalitis virus to Vero cells

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Changes in the dengue virus major envelope protein on passaging and their localization on the three-dimensional structure of the protein

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Determinants in the envelope E protein and viral RNA helicase NS3 that influence the induction of apoptosis in response to infection with dengue type 1 virus.

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Chimeric dengue type 2 (vaccine strain PDK-53)/dengue type 1 virus as a potential candidate dengue type 1 virus vaccine

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Single mutation in the flavivirus envelope protein hinge region increases neurovirulence for mice and monkeys but decreases viscerotropism for monkeys: relevance to development and safety testing of live, attenuated vaccines

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A single amino acid substitution in the envelope protein of chimeric yellow fever-dengue 1 vaccine virus reduces neurovirulence for suckling mice and viremia/viscerotropism for monkeys

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Amino acid changes in the recombinant Dengue 3 Envelope domain III determine its antigenicity and immunogenicity in mice.

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Mutational analysis of a neutralization epitope on the dengue type 2 virus (DEN2) envelope protein: monoclonal antibody resistant DEN2/DEN4 chimeras exhibit reduced mouse neurovirulence

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An external loop region of domain III of dengue virus type 2 envelope protein is involved in serotype-specific binding to mosquito but not mammalian cells

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The NS1 protein of tick-borne encephalitis virus forms multimeric species upon secretion from the host cell

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Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication

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Cell surface expression of yellow fever virus non-structural glycoprotein NS1: consequences of interaction with antibody

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High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever

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The effects of site-directed mutagenesis on the dimerization and secretion of the NS1 protein specified by dengue virus

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Attenuation markers of a candidate dengue type 2 vaccine virus, strain 16681 (PDK-53), are defined by mutations in the 5' noncoding region and nonstructural proteins 1 and 3

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Mutations which enhance the replication of dengue virus type 4 and an antigenic chimeric dengue virus type 2/4 vaccine candidate in Vero cells

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Subcellular localization and membrane topology of the Dengue virus type 2 Non-structural protein 4B.

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Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA.

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Inhibition of Alpha/Beta Interferon Signaling by the NS4B Protein of Flaviviruses

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Computer-assisted identification of a putative methyltransferase domain in NS5 protein of flaviviruses and lambda 2 protein of reovirus

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An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization

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Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

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Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides

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De novo initiation of viral RNA-dependent RNA synthesis

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Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerases.

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Mutations in the nonstructural region 5B of hepatitis C virus genotype 1b: their relation to viral load, response to interferon, and the nonstructural region 5A.

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Preparation of an attenuated dengue 4 (341750 Carib) virus vaccine. I. Pre-clinical studies

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Proper processing of dengue virus nonstructural glycoprotein NS1 requires the N-terminal hydrophobic signal sequence and the downstream nonstructural protein NS2a

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Elimination of L-A double-stranded RNA virus of Saccharomyces cerevisiae by expression of gag and gag-pol from an L-A cDNA clone

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Identification of specific nucleotide sequences within the conserved 3'-SL in the dengue type 2 virus genome required for replication

1 reference

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10.1016/J.VACCINE.2009.10.084

1 reference

Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

ResearchGate publication ID

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