Metabolically Stable tert-Butyl Replacement (Q39777809)

14 September 2017

Metabolically Stable tert-Butyl Replacement (English)

1 reference

14 September 2017

David Barnes-Seeman

1

1 reference

14 September 2017

Monish Jain

2

1 reference

14 September 2017

Leslie Bell

3

1 reference

14 September 2017

Suzie Ferreira

4

1 reference

14 September 2017

Scott Cohen

5

1 reference

14 September 2017

Xiao-Hui Chen

6

1 reference

14 September 2017

Jakal Amin

7

1 reference

14 September 2017

Brad Snodgrass

8

1 reference

14 September 2017

Panos Hatsis

9

1 reference

14 September 2017

22 April 2013

1 reference

ACS Medicinal Chemistry Letters

14 September 2017

1 reference

14 September 2017

4

1 reference

14 September 2017

6

1 reference

14 September 2017

514-516

1 reference

Discovery of pyrroloaminopyrazoles as novel PAK inhibitors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027455

Orally bioavailable imidazoazepanes as calcitonin gene-related peptide (CGRP) receptor antagonists: discovery of MK-2918.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027455

Finasteride metabolism and pharmacogenetics: new approaches to personalized prevention of prostate cancer.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027455

Cytochrome p450 and chemical toxicology

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027455

Cytochrome P450 in vitro reaction phenotyping: a re-evaluation of approaches used for P450 isoform identification

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027455

The use of in vitro metabolic stability for rapid selection of compounds in early discovery based on their expected hepatic extraction ratios

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027455

Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027455

Oxetanes in drug discovery: structural and synthetic insights

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027455

Identification of finasteride metabolites in human bile and urine by high-performance liquid chromatography/tandem mass spectrometry.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027455

Biarylpyrazolyl oxadiazole as potent, selective, orally bioavailable cannabinoid-1 receptor antagonists for the treatment of obesity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027455

Imidazopyridines as VLA-4 integrin antagonists

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027455

Spirocyclic oxetanes: synthesis and properties

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027455

Oxetanes as Promising Modules in Drug Discovery

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900702

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ML400045J

1 reference

release_ar7drlvpszevfhulquwqijtvi4

14 September 2017

0 references

1 reference

14 September 2017

1 reference