Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information. (Q39770211)

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English	Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information.	scientific article

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Europe PubMed Central

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4 April 2020

Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information (English)

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4 April 2020

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4 April 2020

Richard S. Judson

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4 April 2020

Grace Patlewicz

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4 April 2020

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Jie Liu

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4 April 2020

Russell S Thomas

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9 May 2016

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4 April 2020

Regulatory Toxicology and Pharmacology

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4 April 2020

79

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4 April 2020

12-24

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4 April 2020

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

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7 January 2021

The challenge of using read-across within the EU REACH regulatory framework; how much uncertainty is too much? Dipropylene glycol methyl ether acetate, an exemplary case study

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Animal use and lessons learned in the U.S. High Production Volume Chemicals Challenge Program

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A framework to facilitate consistent characterization of read across uncertainty

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A strategy for safety assessment of chemicals with data gaps for developmental and/or reproductive toxicity

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7 January 2021

A Stepwise Approach for Defining the Applicability Domain of SAR and QSAR Models

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7 January 2021

Assessment of methods to define the applicability domain of structural alert models.

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7 January 2021

ToxRead: a tool to assist in read across and its use to assess mutagenicity of chemicals

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Matplotlib: A 2D Graphics Environment

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In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project

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7 January 2021

Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management.

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7 January 2021

Integrative chemical-biological read-across approach for chemical hazard classification

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2016.05.008

7 January 2021

TIMES-SS—A promising tool for the assessment of skin sensitization hazard. A characterization with respect to the OECD validation principles for (Q)SARs and an external evaluation for predictivity

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2016.05.008

7 January 2021

Toxmatch–a new software tool to aid in the development and evaluation of chemically similar groups

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2016.05.008

7 January 2021

Use of category approaches, read-across and (Q)SAR: general considerations

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2016.05.008

7 January 2021

Read-across approaches--misconceptions, promises and challenges ahead

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2016.05.008

7 January 2021

TIMES-SS--recent refinements resulting from an industrial skin sensitisation consortium.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2016.05.008

7 January 2021

Building scientific confidence in the development and evaluation of read-across.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2016.05.008

7 January 2021

Extended-connectivity fingerprints

1 reference

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7 January 2021

A strategy for structuring and reporting a read-across prediction of toxicity

1 reference

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7 January 2021

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA).

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2016.05.008

7 January 2021

A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2016.05.008

7 January 2021

Current status of methods for defining the applicability domain of (quantitative) structure-activity relationships. The report and recommendations of ECVAM Workshop 52

1 reference

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7 January 2021

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10.1016/J.YRTPH.2016.05.008

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27174420%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27174420%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

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