Silibinin induces protective superoxide generation in human breast cancer MCF-7 cells (Q39766045)

14 September 2017

Silibinin induces protective superoxide generation in human breast cancer MCF-7 cells (English)

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14 September 2017

Hong-Jun Wang

1

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14 September 2017

Yuan-Yuan Jiang

2

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14 September 2017

Xiao-Feng Wei

3

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14 September 2017

Huai Huang

4

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14 September 2017

Shin-Ichi Tashiro

5

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14 September 2017

Satoshi Onodera

6

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14 September 2017

Takashi Ikejima

7

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14 September 2017

1 January 2010

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14 September 2017

Free Radical Research

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14 September 2017

44

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14 September 2017

1

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14 September 2017

90-100

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Antioxidant properties of silybin glycosides

14 September 2017

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https://api.crossref.org/works/10.3109%2F10715760903300717

Toward the definition of the mechanism of action of silymarin: activities related to cellular protection from toxic damage induced by chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Restoration of the cellular thiol status of peritoneal macrophages from CAPD patients by the flavonoids silibinin and silymarin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Multitargeted therapy of cancer by silymarin

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715760903300717

Inhibition of insulin-like growth factor 1 receptor signaling enhanced silibinin-induced activation of death receptor and mitochondrial apoptotic pathways in human breast cancer MCF-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

How mitochondria produce reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Mechanism of thiazolidinedione-dependent cell death in Jurkat T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715760903300717

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Reactive oxygen species as double-edged swords in cellular processes: low-dose cell signaling versus high-dose toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Sensitive and rapid quantitation of oxygen reactive species formation in rat synaptosomes

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715760903300717

Fluorescent cationic probes of mitochondria. Metrics and mechanism of interaction

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715760903300717

Cytochrome c in the apoptotic and antioxidant cascades

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715760903300717

The effect of inhibitors on the oxygen kinetics of cytochrome c oxidase

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715760903300717

The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715760903300717

Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Role of Bcl-2 family proteins in apoptosis: apoptosomes or mitochondria?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Reactive oxygen species (ROS) control the expression of Bcl-2 family proteins by regulating their phosphorylation and ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

The mitochondrial death/life regulator in apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Generating, partitioning, targeting and functioning of superoxide in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Pyrroles and other heterocycles as inhibitors of p38 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Glutathione, free radicals and chemotherapeutic agents. Mechanisms of free-radical induced toxicity and glutathione-dependent protection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Free radical scavenging reactions and antioxidant activities of silybin: mechanistic aspects and pulse radiolytic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Membrane depolarization of isolated rat liver mitochondria attenuates permeability transition pore opening and oxidant production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

FAK integrates growth-factor and integrin signals to promote cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Silibinin: a thorny therapeutic for EGF-R expressing tumors?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Silibinin suppresses human osteosarcoma MG-63 cell invasion by inhibiting the ERK-dependent c-Jun/AP-1 induction of MMP-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Superoxide and hydrogen peroxide in relation to mammalian cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells (a review)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Sphingosine 1-phosphate induces EGFR expression via Akt/NF-kappaB and ERK/AP-1 pathways in rat vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Angiotensin II enhances EGF receptor expression levels via ROS formation in HaCaT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Oxidative stress activates insulin-like growth factor I receptor protein expression, mediating cardiac hypertrophy induced by thyroxine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Mitochondrial ROS initiate phosphorylation of p38 MAP kinase during hypoxia in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Reactive oxygen species stimulate insulin-like growth factor I synthesis in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

Superoxide Radical Formation by Pure Complex I (NADH:Ubiquinone Oxidoreductase) fromYarrowia lipolytica

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715760903300717

10.3109/10715760903300717

21 January 2018

Identifiers

DOI

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14 September 2017

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