The G1057D polymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian Indians (Q39753644)

14 September 2017

title

The G1057D polymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian Indians (English)

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14 September 2017

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Bodhini D

1

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14 September 2017

Radha V

2

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14 September 2017

Deepa R

3

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14 September 2017

Ghosh S

4

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14 September 2017

Majumder PP

5

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14 September 2017

Rao MR

6

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14 September 2017

Mohan V

7

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14 September 2017

language of work or name

English

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publication date

25 April 2006

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International Journal of Obesity

14 September 2017

published in

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14 September 2017

volume

31

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14 September 2017

issue

1

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14 September 2017

page(s)

97-102

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https://scigraph.springernature.com/pub.10.1038/sj.ijo.0803356

14 September 2017

exact match

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cites work

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Disruption of IRS-2 causes type 2 diabetes in mice

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Insulin receptor substrate-2 amino acid polymorphisms are not associated with random type 2 diabetes among Caucasians

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Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity.

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New amino acid substitutions in the IRS-2 gene in Finnish and Chinese subjects with late-onset type 2 diabetes

21 January 2018

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The prevalent Gly1057Asp polymorphism in the insulin receptor substrate-2 gene is not associated with impaired insulin secretion

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJO.0803356

Interaction between the G1057D variant of IRS-2 and overweight in the pathogenesis of type 2 diabetes.

21 January 2018

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Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity

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Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

21 January 2018

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Risk of noninsulin dependent diabetes mellitus conferred by obesity and central adiposity in different ethnic groups: a comparative analysis between Asian Indians, Mexican Americans and Whites

21 January 2018

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Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation

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Polymorphisms of the insulin receptor substrate-2 in patients with type 2 diabetes.

21 January 2018

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The haplotypes of the IRS-2 gene affect insulin sensitivity in Japanese patients with type 2 diabetes.

21 January 2018

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Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes

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Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus

21 January 2018

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Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome

21 January 2018

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Molecular heterosis: a review

21 January 2018

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Ethnic India: A Genomic View, With Special Reference to Peopling and Structure

21 January 2018

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Genomic control, a new approach to genetic-based association studies

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Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

21 January 2018

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7 January 2021

Serum immunoreactive insulin responses to a glucose load in Asian Indian and European type 2 (non-insulin-dependent) diabetic patients and control subjects

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7 January 2021

Insulin resistance in patients of Asian Indian and European origin with non-insulin dependent diabetes

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7 January 2021

Metabolic and clinical characteristics of south Asians and Europeans in Coventry

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7 January 2021

The Gly1057Asp polymorphism in IRS-2 interacts with obesity to affect beta cell function

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https://api.crossref.org/works/10.1038%2FSJ.IJO.0803356

7 January 2021

Complex haplotypes of IRS2 gene are associated with severe obesity and reveal heterogeneity in the effect of Gly1057Asp mutation.

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https://api.crossref.org/works/10.1038%2FSJ.IJO.0803356

7 January 2021

Identifiers

DOI

10.1038/SJ.IJO.0803356

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14 September 2017

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