Aminochrome induces disruption of actin, alpha-, and beta-tubulin cytoskeleton networks in substantia-nigra-derived cell line (Q39750114)

14 September 2017

Aminochrome induces disruption of actin, alpha-, and beta-tubulin cytoskeleton networks in substantia-nigra-derived cell line (English)

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14 September 2017

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Irmgard Paris

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14 September 2017

Carolina Perez-Pastene

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14 September 2017

Sergio Cardenas

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14 September 2017

Patricio Iturriaga-Vasquez

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14 September 2017

Patricia Muñoz

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14 September 2017

Eduardo Couve

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14 September 2017

Pablo Caviedes

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14 September 2017

Juan Segura-Aguilar

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14 September 2017

20 January 2010

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Neurotoxicity Research

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82-92

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https://scigraph.springernature.com/pub.10.1007/s12640-009-9148-4

14 September 2017

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Copper neurotoxicity in rat substantia nigra and striatum is dependent on DT-diaphorase inhibition

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Inhibition of VMAT-2 and DT-diaphorase induce cell death in a substantia nigra-derived cell line--an experimental cell model for dopamine toxicity studies

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Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

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Structural plasticity in actin and tubulin polymer dynamics

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Dopamine-dependent iron toxicity in cells derived from rat hypothalamus

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Dicoumarol impairs mitochondrial electron transport and pyrimidine biosynthesis in human myeloid leukemia HL-60 cells.

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Actin cytoskeleton: a signaling sensor in cell volume regulation

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On the mechanism of the Mn3(+)-induced neurotoxicity of dopamine:prevention of quinone-derived oxygen toxicity by DT diaphorase and superoxide dismutase

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Dopamine-derived dopaminochrome promotes H(2)O(2) release at mitochondrial complex I: stimulation by rotenone, control by Ca(2+), and relevance to Parkinson disease

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Kinetic and structural analysis of the early oxidation products of dopamine: analysis of the interactions with alpha-synuclein.

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Molecular and neurochemical mechanisms in PD pathogenesis.

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Superoxide dismutase and catalase enhance autoxidation during one-electron reduction of aminochrome by NADPH-cytochrome P-450 reductase

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Plasma membrane tubulin

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Actin in axons: stable scaffolds and dynamic filaments

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The cytoskeletal architecture of the presynaptic terminal and molecular structure of synapsin 1.

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Monoamine transporter inhibitors and norepinephrine reduce dopamine-dependent iron toxicity in cells derived from the substantia nigra

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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12 December 2020

Copper neurotoxicity is dependent on dopamine-mediated copper uptake and one-electron reduction of aminochrome in a rat substantia nigra neuronal cell line

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12 December 2020

Inhibition of DT-diaphorase is a requirement for Mn(III) to produce a 6-OH-dopamine like rotational behaviour

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Disruption of the interaction of alpha-synuclein with microtubules enhances cell surface recruitment of the dopamine transporter

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The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease

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The catecholaminergic RCSN-3 cell line: a model to study dopamine metabolism

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Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy

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Neonatal dopamine depletion induces changes in morphogenesis and gene expression in the developing cortex.

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Modulation of alpha-synuclein expression in transgenic animals for modelling synucleinopathies--is the juice worth the squeeze?

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New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals

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12 December 2020

Role of microtubules and actin filaments in the movement of mitochondria in the axons and dendrites of cultured hippocampal neurons

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12 December 2020

Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons

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12 December 2020

Enzymatic oxidation of dopamine: the role of prostaglandin H synthase

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12 December 2020

Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells

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12 December 2020

Regiospecific attack of nitrogen and sulfur nucleophiles on quinones derived from poison oak/ivy catechols (urushiols) and analogues as models for urushiol-protein conjugate formation

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12 December 2020

On the neurotoxicity mechanism of leukoaminochrome o-semiquinone radical derived from dopamine oxidation: mitochondria damage, necrosis, and hydroxyl radical formation

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Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

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Aminochrome as a preclinical experimental model to study degeneration of dopaminergic neurons in Parkinson's disease

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Copper dopamine complex induces mitochondrial autophagy preceding caspase-independent apoptotic cell death

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The actin cytoskeleton: integrating form and function at the synapse

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Distribution of DT diaphorase in the rat brain: biochemical and immunohistochemical studies

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Metabolic activation of dopamine o-quinones to o-semiquinones by NADPH cytochrome P450 reductase may play an important role in oxidative stress and apoptotic effects

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The neurotoxin, MPP+, induces hyperphosphorylation of Tau, in the presence of alpha-Synuclein, in SH-SY5Y neuroblastoma cells

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Human class Mu glutathione transferases, in particular isoenzyme M2-2, catalyze detoxication of the dopamine metabolite aminochrome

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Comparative study of cyanotoxins affecting cytoskeletal and chromatin structures in CHO-K1 cells.

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Dopamine induces supernumerary centrosomes and subsequent cell death through Cdk2 up-regulation in dopaminergic neuronal cells

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Covalent arylation of metallothionein by oxidized dopamine products: a possible mechanism for zinc-mediated enhancement of dopaminergic neuron survival

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12 December 2020

Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations.

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12 December 2020

10.1007/S12640-009-9148-4

Identifiers

DOI

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14 September 2017

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