An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, downregulated in Barrett's oesophagus, which regulates NF-kappaB activation and cytokine levels. (Q39742473)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, downregulated in Barrett's oesophagus, which regulates NF-kappaB activation and cytokine levels.	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, downregulated in Barrett's oesophagus, which regulates NF-kappaB activation and cytokine levels (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1 reference

based on heuristic

inferred from title

John V Reynolds

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Sinéad M. Smith

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Shane P Duggan

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Fiona M Behan

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Murat Kirca

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Dermot Kelleher

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

0 references

publication date

5 February 2010

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

31

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

936-945

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

describes a project that uses

0 references

0 references

Proinflammatory cytokine and nuclear factor kappa-B expression along the inflammation-metaplasia-dysplasia-adenocarcinoma sequence in the esophagus

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Increased expression and secretion of interleukin-6 in patients with Barrett's esophagus.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Gastroesophageal reflux disease-associated esophagitis induces endogenous cytokine production leading to motor abnormalities

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

A COX-2 inhibitor prevents the esophageal inflammation-metaplasia-adenocarcinoma sequence in rats

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Deoxycholic acid causes DNA damage in colonic cells with subsequent induction of caspases, COX-2 promoter activity and the transcription factors NF-kB and AP-1.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Promoting effect of bile acids on colon carcinogenesis after intrarectal instillation of N-methyl-N'-nitro-N-nitrosoguanidine in rats.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Bile acid deoxycholate induces differential subcellular localisation of the PKC isoenzymes beta 1, epsilon and delta in colonic epithelial cells in a sodium butyrate insensitive manner

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

The bile acid deoxycholic acid (DCA) at neutral pH activates NF-kappaB and induces IL-8 expression in oesophageal cells in vitro

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to barrett's esophagus.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Transcriptional profiling suggests that Barrett's metaplasia is an early intermediate stage in esophageal adenocarcinogenesis.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Low pH induces co-ordinate regulation of gene expression in oesophageal cells.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

In vitro acid exposure has a differential effect on apoptotic and proliferative pathways in a Barrett's adenocarcinoma cell line

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Bile acids as carcinogens in human gastrointestinal cancers

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Bile Acid Regulation of C/EBPβ, CREB, and c-Jun Function, via the Extracellular Signal-Regulated Kinase and c-Jun NH2-Terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

COX-2 induction by unconjugated bile acids involves reactive oxygen species-mediated signalling pathways in Barrett's oesophagus and oesophageal adenocarcinoma

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett's oesophagus

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

SINK Is a p65-interacting Negative Regulator of NF-κB-dependent Transcription

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Human tribbles, a protein family controlling mitogen-activated protein kinase cascades

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

NF-kappaB activation in esophageal adenocarcinoma: relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Activated nuclear factor-kappa B and cytokine profiles in the esophagus parallel tumor regression following neoadjuvant chemoradiotherapy

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ036

21 January 2018

Identifiers

10.1093/CARCIN/BGQ036

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139130%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39742473&oldid=2089256560"