Metabolic activation of mutagenic heterocyclic aromatic amines from protein pyrolysates (Q39733665)

14 September 2017

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title

Metabolic activation of mutagenic heterocyclic aromatic amines from protein pyrolysates (English)

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14 September 2017

Kato R

1

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PubMed ID

3519087

14 September 2017

language of work or name

English

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publication date

1 January 1986

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Critical Reviews in Toxicology

14 September 2017

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14 September 2017

16

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14 September 2017

4

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14 September 2017

307-348

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Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals

14 September 2017

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Mutagenic Factors in Cooked Foods

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Carcinogenicity in mice of mutagenic compounds from a tryptophan pyrolyzate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Isolation and structure studies of mutagenic principles in amino acid pyrolysates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Metabolic activation of mutagenic tryptophan pyrolysis products (Trp-P-1 and Trp-P-2) by a purified cytochrome P-450-dependent monooxygenase system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Immunological analysis of the roles of two major types of cytochrome P-450 in mutagenesis of compounds isolated from pyrolysates.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Formation of mutagenic derivatives from tryptophan pyrolysis products (Trp P1 and Trp P2) by rat intestinal S9 fraction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Isolation and characterization of active metabolites of tryptophan-pyrolysate mutagen, TRP-P-2, formed by rat liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Activation of a mutagen, 3-amino-1-methyl-5H-pyrido[4,3-b]indole. Identification of 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole and its reacion with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Effects of ascorbic acid on the nonenzymatic binding to DNA and the mutagenicity of N-hydroxylated metabolite of a tryptophan-pyrolysis product

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Metabolic activation of trp-P-2, a mutagenic amine from tryptophan-pyrolysate, by liver microsomes from 3-methylcholanthrene-responsive and non-responsive mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Pyrolysis products from amino acids and protein: Highest mutagenicity requires cytochrome P 1 -450

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Metabolic activation of glutamic acid pyrolysis products, 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole and 2-amino-dipyrido[1,2-a:3',2'-d]imidazole, by purified cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Sequence selective modification of DNA with muta-carcinogenic 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Effect of methyl substitution on mutagenicity of 2-aminodipyrido.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Mutagenicity of amino-α-carbolines in pyrolysis products of soybean globulin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Metabolic activation of 2-amino-9H-pyrido[2,3-b]indole by rat-liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Metabolic activation of a tryptophan pyrolysis product, 3-amino-1-methyl-5H-pyrido[4,3-b]indole(TRP-P-2) by isolated rat liver nuclei.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Mutagenic activation of 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole(Trp-P-1) and 3-amino-1-methyl-5H-pyrido(4,3-b)indole (Trp-P-2) by primary cultures of adult rat hepatocytes: effect of Aroclor induction in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Activation of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-aminofluorene for bacterial mutagenesis by primary monolayer cultures of adult rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Distribution of the carcinogenic tryptophan pyrolysis product Trp-P-1 in control, 9-hydroxyellipticine and beta-naphthoflavone pretreated mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Anti-mutagenic action of vegetable factor(s) on the mutagenic principle of tryptophan pyrolysate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Adsorption of pyrolysate mutagens by vegetable fibers.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Degradation of mutagens from pyrolysates of tryptophan, glutamic acid and globulin by myeloperoxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Inhibition of the mutagenicity of amino acid pyrolysis products by hemin and other biological pyrrole pigments.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Inhibitory effect of the ether extract of human feces on activities of mutagens: inhibition by oleic and linoleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Interactions between the active metabolite of tryptophan pyrolysate mutagen, N-hydroxy-Trp-P-2, and lipids: the role of lipid peroxides in the conversion of N-hydroxy-Trp-P-2 to non-reactive forms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Differences in effects of norharman with various classes of chemical mutagens and amounts of S-9

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Effects of the comutagens, harman and norharman, on the interaction of a tryptophan pyrolysis product, 3-amino-1-methyl-5H-pyrido(4,3-b)indole with DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Actions of amino-beta-carbolines on induction of sister-chromatid exchanges

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Effect of norharman on DNA strand breaks and mutation of Chinese hamster V79 cells by chemical carcinogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

The enhancing effect of cysteine and its derivatives on the mutagenic activities of the tryptophan-pyrolysis products, Trp-P-1 and Trp-P-2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Specificity of rat liver cytochrome P-450 isozymes in the mutagenic activation of benzo[a]pyrene, aromatic amines and aflatoxin B1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Enzymatic N-acetylation of carcinogenic aromatic amines by liver cytosol of species displaying different organ susceptibilities

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Acetylation, deacetylation and acyltransfer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Mutagenicities of gamma-carboline derivatives related to potent mutagens found in tryptophan pyrolysates.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

N-hydroxylation of carcinogenic and mutagenic aromatic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

In vitro metabolism of o-aminoazotoluene and mutagenesis of Salmonella by the metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Activation and detoxication of N-hydroxy-Trp-P-2 by glutathione and glutathione transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Inhibition of glutathione-S-aryltransferase from rat liver by organogermanium, lead and tin compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Influence of conjugation reactions on the mutagenicity of aromatic amines.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Formation and identification of glutathione conjugates from 2-nitrosofluorene and N-hydroxy-2-aminofluorene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Identification of glutathione conjugates formed from N-hydroxy-2-acetylaminofluorene in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Glutathione conjugation of arylnitroso compound: detection and monitoring labile intermediates in situ inside a fast atom bombardment mass spectrometer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Effect of glutathione and uridine-5'-diphosphoglucuronic acid on the mutagenicity of tryptophan pyrolysis products (Trp-P-1 and Trp-P-2) by rat-liver and -intestine S9 fraction.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Ascorbic acid inhibits covalent binding of enzymatically generated 2-acetyl-aminofluororene-N-sulfate to DNA under conditions in which it increases mutagenesis in salmonella TA-1538

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Covalent binding of N-hydroxy-Trp-P-2 to DNA by cytosolic proline-dependent system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Seryl-tRNA synthetase and activation of the carcinogen 4-nitroquinoline 1-oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

DNA binding of N-hydroxy-Trp-P-2 and N-hydroxy-Glu-P-1 by acetyl-CoA dependent enzyme in mammalian liver cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Metabolic activation of mutagenic N-hydroxyarylamines by O-acetyltransferase in Salmonella typhimurium TA98.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

The extraordinary mutagenicity of nitropyrenes in bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

A cautionary note the use of nitroreductase-deficient strains of Salmonella typhimurium for the detection of nitroarenes as mutagens in complex mixtures including diesel exhausts.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Syntheses of hydroxyamino, nitroso and nitro derivatives of Trp-P-2 and Glu-P-1, amino acid pyrolysate mutagens, and their direct mutagenicities towards Salmonella typhimurium TA98 and TA98NR

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Evidence for the existence of a family of bacterial nitroreductases capable of activating nitrated polycyclics to mutagens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Esterification of arylhydroxylamines: evidence for a specific gene product in mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Ultimate forms of mutagenic and carcinogenic heterocyclic amines produced by pyrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Mechanism of activation of proximate mutagens in Ames' tester strains: the acetyl-CoA dependent enzyme in Salmonella typhimurium TA98 deficient in TA98/1,8-DNP6 catalyzes DNA-binding as the cause of mutagenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Enzymic N-acetylation of N-hydroxy-2-aminofluorene by liver cytosol from various species

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Mutagenesis of amino acid pyrolysis products in Chinese hamster V79 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Mutagenic activity of heterocyclic amines in Chinese hamster lung cells with diphtheria toxin resistance as a marker

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Cytochrome P-450 as a determinant of sex difference of drug metabolism in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

The effect of acetyl-CoA supplementation on the mutagenicity of benzidines in the Ames assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

Mutagenicity of benzidine and 4-aminobiphenyl after metabolic activation with isolated hepatocytes and liver 9000 X g supernatant from rat, hamster and guinea pig.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

STRUCTURE AND CHEMICAL SYNTHESIS OF ME-IQ, A POTENT MUTAGEN ISOLATED FROM BROILED FISH

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448609037466

10.3109/10408448609037466

21 January 2018

Identifiers

DOI

0 references

PubMed ID

3519087

1 reference

PubMed ID

3519087