Conjugation of Smt3 to dorsal may potentiate the Drosophila immune response (Q39695418)

14 September 2017

Conjugation of Smt3 to dorsal may potentiate the Drosophila immune response (English)

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14 September 2017

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1 reference

GOA release 2020-03-11

Lesswright Dmel_CG3018

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GOA release 2020-03-11

Smt3 Dmel_CG4494

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GOA release 2020-03-11

author name string

Vinay Bhaskar

series ordinal

1

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14 September 2017

Matthew Smith

series ordinal

2

1 reference

14 September 2017

Albert J Courey

series ordinal

3

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14 September 2017

language of work or name

English

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publication date

1 January 2002

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Molecular and Cellular Biology

14 September 2017

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14 September 2017

22

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14 September 2017

492-504

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14 September 2017

2

1 reference

describes a project that uses

14 September 2017

529SU

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cites work

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Ubc9 interacts with a nuclear localization signal and mediates nuclear localization of the paired-like homeobox protein Vsx-1 independent of SUMO-1 modification

14 September 2017

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Sumo-1 modification regulates the DNA binding activity of heat shock transcription factor 2, a promyelocytic leukemia nuclear body associated transcription factor

14 September 2017

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Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity.

14 September 2017

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SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting

14 September 2017

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Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1).

14 September 2017

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Yeast Ulp1, an Smt3-specific protease, associates with nucleoporins

14 September 2017

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A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity

14 September 2017

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RING finger proteins: mediators of ubiquitin ligase activity

14 September 2017

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Toll-like receptors in the induction of the innate immune response

14 September 2017

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A common motif within the negative regulatory regions of multiple factors inhibits their transcriptional synergy

14 September 2017

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Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast

14 September 2017

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SUMO-1 conjugation to human DNA topoisomerase II isozymes

14 September 2017

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Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

14 September 2017

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Ubiquitin-like proteins: new wines in new bottles

14 September 2017

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Role of SUMO-1-modified PML in nuclear body formation

14 September 2017

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SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Signaling mechanisms in the antimicrobial host defense of Drosophila

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Control of development and immunity by rel transcription factors in Drosophila

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

SUMO-1 modification activates the transcriptional response of p53

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Ubc9 interacts with the androgen receptor and activates receptor-dependent transcription

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Modulation of TEL transcription activity by interaction with the ubiquitin-conjugating enzyme UBC9

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Viral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruption

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Toll receptor-mediated Drosophila immune response requires Dif, an NF-kappaB factor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

A new protease required for cell-cycle progression in yeast

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

A role for Groucho tetramerization in transcriptional repression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Dorsal-mediated repression requires the formation of a multiprotein repression complex at the ventral silencer.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Drosophila immune responses as models for human immunity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Ubch9 conjugates SUMO but not ubiquitin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Conversion of dorsal from an activator to a repressor by the global corepressor Groucho

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Direct involvement of the ubiquitin-conjugating enzyme Ubc9/Hus5 in the degradation of IkappaBalpha

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

A direct contact between the dorsal rel homology domain and Twist may mediate transcriptional synergy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Regulated nuclear import of the Drosophila rel protein dorsal: structure-function analysis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

A functional interaction between dorsal and components of the Smt3 conjugation machinery

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Lipopolysaccharide-activated kinase, an essential component for the induction of the antimicrobial peptide genes in Drosophila melanogaster cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

The binding interface between an E2 (UBC9) and a ubiquitin homologue (UBL1).

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

The Drosophila semushi mutation blocks nuclear import of bicoid during embryogenesis.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

The dorsoventral signal transduction pathway and the Rel-like transcription factors in Drosophila

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

The control of cell fate along the dorsal-ventral axis of the Drosophila embryo.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

The Drosophila UBC9 homologue lesswright mediates the disjunction of homologues in meiosis I.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

Interaction and specificity of Rel-related proteins in regulating Drosophila immunity gene expression

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

The functional domains of the Drosophila morphogen dorsal: evidence from the analysis of mutants

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139748

SUMO conjugation and deconjugation

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11756545

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Mdm-2 amino terminus is required for Mdm2 binding and SUMO-1 conjugation by the E2 SUMO-1 conjugating enzyme Ubc9

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11756545

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.22.2.492-504.2002

1 reference

14 September 2017

1 reference

14 September 2017

1 reference