Sclerostin is a direct target of osteoblast-specific transcription factor osterix (Q39659778)

13 September 2017

Sclerostin is a direct target of osteoblast-specific transcription factor osterix (English)

1 reference

transcriptional activation

13 September 2017

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20816666

6 July 2024

author name string

Fan Yang

1

1 reference

13 September 2017

Wanjin Tang

2

1 reference

13 September 2017

Sarah So

3

1 reference

13 September 2017

Benoit de Crombrugghe

4

1 reference

13 September 2017

Chi Zhang

5

1 reference

13 September 2017

language of work or name

English

0 references

publication date

8 September 2010

1 reference

full work available at URL

13 September 2017

https://europepmc.org/articles/pmc4041335?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20816666

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20816666/?tool=EBI

6 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20816666

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20816666/pdf/?tool=EBI

6 July 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20816666

https://europepmc.org/articles/PMC4041335

6 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20816666

https://europepmc.org/articles/PMC4041335?pdf=render

6 July 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20816666

https://doi.org/10.1016/j.bbrc.2010.08.128

6 July 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20816666

https://api.elsevier.com/content/article/PII:S0006291X10016499?httpAccept=text/xml

6 July 2024

1 reference

10.1016/J.BBRC.2010.08.128

Crossref

DOI

https://api.crossref.org/works/10.1016/J.BBRC.2010.08.128

https://api.elsevier.com/content/article/PII:S0006291X10016499?httpAccept=text/plain

6 July 2024

1 reference

10.1016/J.BBRC.2010.08.128

Crossref

DOI

https://api.crossref.org/works/10.1016/J.BBRC.2010.08.128

Biochemical and Biophysical Research Communications

6 July 2024

published in

1 reference

13 September 2017

400

1 reference

13 September 2017

4

1 reference

13 September 2017

684-688

1 reference

Transcriptional regulation of osteoblasts

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Wnt signaling: a win for bone

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Osteocyte-derived sclerostin inhibits bone formation: its role in bone morphogenetic protein and Wnt signaling.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Wnt signaling: a key regulator of bone mass

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Regulation of bone mass by Wnt signaling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Sequential roles of Hedgehog and Wnt signaling in osteoblast development

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

High bone mass in mice expressing a mutant LRP5 gene

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

The binding between sclerostin and LRP5 is altered by DKK1 and by high-bone mass LRP5 mutations

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

SOST is a target gene for PTH in bone

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Role of Wnt signaling in bone remodeling and repair

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

Patients with Van Buchem disease, an osteosclerotic genetic disease, have elevated bone formation markers, higher bone density, and greater derived polar moment of inertia than normal

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041335

10.1016/J.BBRC.2010.08.128

21 August 2018

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DOI

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release_wpu4h7kxgrcyfjmtb42gir4gqy

13 September 2017

1 reference

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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13 September 2017

1 reference