Clostridium septicum alpha-toxin is active against the parasitic protozoan Toxoplasma gondii and targets members of the SAG family of glycosylphosphatidylinositol-anchored surface proteins. (Q39655745)

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scientific article published on August 2002

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English	Clostridium septicum alpha-toxin is active against the parasitic protozoan Toxoplasma gondii and targets members of the SAG family of glycosylphosphatidylinositol-anchored surface proteins.	scientific article published on August 2002

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scholarly article

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10 November 2019

Clostridium septicum alpha-toxin is active against the parasitic protozoan Toxoplasma gondii and targets members of the SAG family of glycosylphosphatidylinositol-anchored surface proteins (English)

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10 November 2019

Toxoplasma gondii

0 references

Clostridium septicum

object named as

Clostridium septicum

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based on heuristic

inferred from title

5

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10 November 2019

author name string

Michael J Wichroski

1

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10 November 2019

Jody A Melton

2

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10 November 2019

Carolyn G Donahue

3

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10 November 2019

Rodney K Tweten

4

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publication date

1 August 2002

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10 November 2019

Infection and Immunity

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10 November 2019

70

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8

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10 November 2019

4353-4361

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10 November 2019

Lytic cycle of Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

Recent developments in the cell biology and biochemistry of glycosylphosphatidylinositol lipids (review).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

Identification and molecular characterization of GRA8, a novel, proline-rich, dense granule protein of Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

The structure, biosynthesis and functions of glycosylphosphatidylinositol anchors, and the contributions of trypanosome research.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

The surface of Toxoplasma tachyzoites is dominated by a family of glycosylphosphatidylinositol-anchored antigens related to SAG1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

A pore-forming toxin interacts with a GPI-anchored protein and causes vacuolation of the endoplasmic reticulum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

Clostridium septicum alpha-toxin is proteolytically activated by furin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

Organization of two invariant surface glycoproteins in the surface coat of Trypanosoma brucei.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

Similarities between the primary structures of two distinct major surface proteins of Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

The primary structure of Clostridium septicum alpha-toxin exhibits similarity with that of Aeromonas hydrophila aerolysin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

Insertional mutagenesis and marker rescue in a protozoan parasite: cloning of the uracil phosphoribosyltransferase locus from Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

Phase separation of integral membrane proteins in Triton X-114 solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

Strain-specific antigens of Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

Purification and characterization of the lethal toxin (alpha-toxin) of Clostridium septicum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

How does Toxoplasma gondii enter host cells?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

The cytolytic toxin aerolysin must aggregate to disrupt erythrocytes, and aggregation is stimulated by human glycophorin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

Quantitative Studies of the Mutagenesis of Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

14 September 2017

The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

25 September 2017

Glycosyl-phosphatidylinositol molecules of the parasite and the host

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

25 September 2017

The nuclear envelope serves as an intermediary between the ER and Golgi complex in the intracellular parasite Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

15 June 2018

The surface of Toxoplasma: more and less

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

15 June 2018

Glycosylphosphatidylinositol anchors of membrane glycoproteins are binding determinants for the channel-forming toxin aerolysin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

15 June 2018

Evidence for N-linked glycosylation in Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

15 June 2018

Isolation and characterization of a monoclonal anti-P30 antibody resistant mutant of Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

15 June 2018

Protection of mice from fatal Toxoplasma gondii infection by immunization with p30 antigen in liposomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

15 June 2018

Biosynthesis of glycolipid precursors for glycosylphosphatidylinositol membrane anchors in a Toxoplasma gondii cell-free system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

15 June 2018

Two glycoforms are present in the GPI-membrane anchor of the surface antigen 1 (P30) of Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

21 August 2018

Characterization of the subpellicular network, a filamentous membrane skeletal component in the parasite Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

21 August 2018

Toxoplasma gondii: identification of a developmentally regulated family of genes related to SAG2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

21 August 2018

Targeted disruption of the glycosylphosphatidylinositol-anchored surface antigen SAG3 gene in Toxoplasma gondii decreases host cell adhesion and drastically reduces virulence in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

21 August 2018

Clostridium septicum alpha toxin uses glycosylphosphatidylinositol-anchored protein receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

21 August 2018

Expression and properties of an aerolysin--Clostridium septicum alpha toxin hybrid protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

21 August 2018

Molecular structure of the "low molecular weight antigen" of Toxoplasma gondii: a glucose alpha 1-4 N-acetylgalactosamine makes free glycosyl-phosphatidylinositols highly immunogenic.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

21 August 2018

Generation of a membrane-bound, oligomerized pre-pore complex is necessary for pore formation by Clostridium septicum alpha toxin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

21 August 2018

Toxoplasma gondii: characterization of a mutant resistant to 6-thioxanthine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128134

21 August 2018

96-Well plates providing high optical resolution for high-throughput, immunofluorescence-based screening of monoclonal antibodies against Toxoplasma gondii

1 reference

https://pubmed.ncbi.nlm.nih.gov/12117945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane glycoprotein receptor and hole-forming properties of a cytolytic protein toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12117945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of a major membrane protein of Toxoplasma gondii by immunoabsorption with a monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/12117945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are rhoptries of Coccidia really extrusomes?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12117945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of stage-specific sporozoite antigens of Toxoplasma gondii by monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12117945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surface antigens of Toxoplasma gondii

1 reference

https://pubmed.ncbi.nlm.nih.gov/12117945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous, nontraumatic gangrene due to Clostridium septicum

1 reference

https://pubmed.ncbi.nlm.nih.gov/12117945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A family of glycolipids from Toxoplasma gondii. Identification of candidate glycolipid precursor(s) for Toxoplasma gondii glycosylphosphatidylinositol membrane anchors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12117945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural analysis of glycosyl-phosphatidylinositol membrane anchor of the Toxoplasma gondii tachyzoite surface glycoprotein gp23

1 reference

https://pubmed.ncbi.nlm.nih.gov/12117945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and mechanism of Clostridium septicum alpha toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12117945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The erythrocyte receptor for the channel-forming toxin aerolysin is a novel glycosylphosphatidylinositol-anchored protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12117945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucosylation of Glycosylphosphatidylinositol Membrane Anchors: Identification of Uridine Diphosphate−Glucose as the Direct Donor for Side Chain Modification inToxoplasma gondiiUsing Carbohydrate Analogues†

1 reference

https://pubmed.ncbi.nlm.nih.gov/12117945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.70.8.4353-4361.2002

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Europe PubMed Central

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10 November 2019

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10 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12117945%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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