Exploring the influence of torsinA expression on protein quality control (Q39619556)

13 September 2017

Exploring the influence of torsinA expression on protein quality control (English)

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13 September 2017

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Kevin A Glenn

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author name string

Kara L Gordon

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1

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PubMed ID

21161590

13 September 2017

Pedro Gonzalez-Alegre

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3

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PubMed ID

21161590

13 September 2017

language of work or name

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16 December 2010

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13 September 2017

Neurochemical Research

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13 September 2017

36

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13 September 2017

3

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13 September 2017

452-459

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https://scigraph.springernature.com/pub.10.1007/s11064-010-0363-4

13 September 2017

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cites work

Primary dystonia: molecules and mechanisms.

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The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

Effects of genetic variations in the dystonia protein torsinA: identification of polymorphism at residue 216 as protein modifier

21 January 2018

1 reference

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The torsin-family AAA+ protein OOC-5 contains a critical disulfide adjacent to Sensor-II that couples redox state to nucleotide binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

Mutant torsinA, responsible for early-onset torsion dystonia, forms membrane inclusions in cultured neural cells

21 January 2018

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Aberrant cellular behavior of mutant torsinA implicates nuclear envelope dysfunction in DYT1 dystonia.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

TorsinA in the nuclear envelope

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

Mislocalization to the nuclear envelope: an effect of the dystonia-causing torsinA mutation.

21 January 2018

1 reference

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A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study

21 January 2018

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TorsinA and heat shock proteins act as molecular chaperones: suppression of alpha-synuclein aggregation

21 January 2018

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Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins

21 January 2018

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TorsinA in PC12 cells: localization in the endoplasmic reticulum and response to stress

21 January 2018

1 reference

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Torsin-mediated protection from cellular stress in the dopaminergic neurons of Caenorhabditis elegans.

21 January 2018

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The early-onset torsion dystonia-associated protein, torsinA, displays molecular chaperone activity in vitro

21 January 2018

1 reference

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RNA interference-mediated inhibition of wild-type Torsin A expression increases apoptosis caused by oxidative stress in cultured cells

21 January 2018

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TorsinA immunoreactivity in inclusion bodies in trinucleotide repeat diseases

21 January 2018

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Biochemical characterization of torsinB.

21 January 2018

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One step at a time: endoplasmic reticulum-associated degradation

21 January 2018

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A trip to the ER: coping with stress

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

SCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

Consequences of the DYT1 mutation on torsinA oligomerization and degradation

21 January 2018

1 reference

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Silencing primary dystonia: lentiviral-mediated RNA interference therapy for DYT1 dystonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

Redox control of endoplasmic reticulum function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

Regulation of the cellular heat shock response in Caenorhabditis elegans by thermosensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

Dystonia-associated mutations cause premature degradation of torsinA protein and cell-type-specific mislocalization to the nuclear envelope

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

A molecular mechanism underlying the neural-specific defect in torsinA mutant mice

21 January 2018

1 reference

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Transcriptional and proteomic profiling in a cellular model of DYT1 dystonia

21 January 2018

1 reference

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Chemical enhancement of torsinA function in cell and animal models of torsion dystonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

A unique redox-sensing sensor II motif in TorsinA plays a critical role in nucleotide and partner binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

TorsinA, the gene linked to early-onset dystonia, is upregulated by the dopaminergic toxin MPTP in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0363-4

TorsinA accumulation in Lewy bodies in sporadic Parkinson's disease

21 January 2018

1 reference

12 December 2020

Torsin A and its torsion dystonia-associated mutant forms are lumenal glycoproteins that exhibit distinct subcellular localizations

1 reference

12 December 2020

Toward therapy for DYT1 dystonia: allele-specific silencing of mutant TorsinA

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12 December 2020

The Caenorhabditis elegans polarity gene ooc-5 encodes a Torsin-related protein of the AAA ATPase superfamily

1 reference

12 December 2020

Overexpression of torsinA in PC12 cells protects against toxicity.

1 reference

12 December 2020

Reduction of the disulfide bond of chromogranin B (secretogranin I) in the trans-Golgi network causes its missorting to the constitutive secretory pathways.

1 reference

12 December 2020

TorsinA protects against oxidative stress in COS-1 and PC12 cells

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12 December 2020

10.1007/S11064-010-0363-4

Identifiers

DOI

1 reference

13 September 2017

1 reference

PubMed ID

21161590