Na(V)1.5 enhances breast cancer cell invasiveness by increasing NHE1-dependent H(+) efflux in caveolae (Q39618185)

13 September 2017

Na(V)1.5 enhances breast cancer cell invasiveness by increasing NHE1-dependent H(+) efflux in caveolae (English)

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13 September 2017

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neoplastic invasiveness

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2

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ORCID Public Data File 2021

13 September 2017

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author name string

L Brisson

1

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13 September 2017

S Calaghan

3

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13 September 2017

P Besson

4

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13 September 2017

J-Y Le Guennec

5

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13 September 2017

S Roger

6

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13 September 2017

J Gore

7

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13 September 2017

language of work or name

English

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publication date

20 December 2010

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13 September 2017

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13 September 2017

30

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13 September 2017

17

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13 September 2017

2070-2076

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https://scigraph.springernature.com/pub.10.1038/onc.2010.574

13 September 2017

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cites work

CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion

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NHE1 promotes invadopodial ECM proteolysis through acidification of the peri-invadopodial space

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Compartmentalisation of cAMP-dependent signalling by caveolae in the adult cardiac myocyte

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The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.

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Functional expression of voltage-gated sodium channels in primary cultures of human cervical cancer

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New functions for the matrix metalloproteinases in cancer progression

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Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis.

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Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer

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Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells.

31 March 2020

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Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles

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Na(+)-H+ antiporter activity in relation to membrane fatty acid composition and cell proliferation.

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Cancer metastasis: building a framework

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Implications of acidic tumor microenvironment for neoplastic growth and cancer treatment: a computer analysis

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Acidic pH enhances the invasive behavior of human melanoma cells

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Acid treatment of melanoma cells selects for invasive phenotypes

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Cysteine cathepsins: multifunctional enzymes in cancer

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Global cancer statistics, 2002

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Involvement of a novel fast inward sodium current in the invasion capacity of a breast cancer cell line

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Voltage-gated sodium channels: new targets in cancer therapy?

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Voltage-gated sodium channels potentiate the invasive capacities of human non-small-cell lung cancer cell lines

31 March 2020

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Protons make tumor cells move like clockwork

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Regulation of Na+/H+ exchanger 1 allosteric balance by its localization in cholesterol- and caveolin-rich membrane microdomains.

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Generation of functional ion-channel tools by E3 targeting.

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Lipid rafts and caveolin-1 are required for invadopodia formation and extracellular matrix degradation by human breast cancer cells

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2010.574

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Dimensions Publication ID

13 September 2017

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