Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63. (Q39612057)

13 September 2017

Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63. (English)

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13 September 2017

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Shu-Er Chow

1

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13 September 2017

Ying-Ling Chang

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2

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13 September 2017

Sun-Fa Chuang

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3

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13 September 2017

Jong-Shyan Wang

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4

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13 September 2017

5 January 2011

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Cancer Chemotherapy and Pharmacology

13 September 2017

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13 September 2017

68

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13 September 2017

4

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13 September 2017

835-845

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https://scigraph.springernature.com/pub.10.1007/s00280-010-1552-1

13 September 2017

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p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

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High level expression of deltaN-p63: a mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)?

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Glycogen synthase kinase-3beta regulates DeltaNp63 gene transcription through the beta-catenin signaling pathway

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Overexpression of delta Np63 in a human nasopharyngeal carcinoma cell line downregulates CKIs and enhances cell proliferation

21 January 2018

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GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis

21 January 2018

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Glycogen synthase kinase 3beta regulates cell death induced by synthetic triterpenoids

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Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

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Aberrant nuclear accumulation of glycogen synthase kinase-3beta in human pancreatic cancer: association with kinase activity and tumor dedifferentiation

21 January 2018

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Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulation

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The glamour and gloom of glycogen synthase kinase-3

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Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell

21 January 2018

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Anticancer effects of wogonin in both estrogen receptor-positive and -negative human breast cancer cell lines in vitro and in nude mice xenografts

21 January 2018

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Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells

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Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells

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Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCdelta phosphorylation

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New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin

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Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis

21 January 2018

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Differential apoptotic effect of wogonin and nor-wogonin via stimulation of ROS production in human leukemia cells

21 January 2018

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The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways

21 January 2018

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Inactivation of glycogen synthase kinase-3beta, a downstream target of the raf-1 pathway, is associated with growth suppression in medullary thyroid cancer cells

21 January 2018

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Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

21 January 2018

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Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event

21 January 2018

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GSK-3 is activated by the tyrosine kinase Pyk2 during LPA1-mediated neurite retraction

21 January 2018

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GSK-3-selective inhibitors derived from Tyrian purple indirubins

21 January 2018

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10.1007/S00280-010-1552-1

21 January 2018

Identifiers

DOI

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release_fakmegcpdzgohivbx4rtj4gmxq

13 September 2017

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Fatcat

https://api.fatcat.wiki/v0/release/fakmegcpdzgohivbx4rtj4gmxq

mapped directly with Wikidata item

24 November 2022

based on heuristic

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