Signal transducer and activator of transcription 3 pathway mediates genipin-induced apoptosis in U266 multiple myeloma cells. (Q39587408)

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23 January 2020

title

Signal transducer and activator of transcription 3 pathway mediates genipin-induced apoptosis in U266 multiple myeloma cells (English)

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23 January 2020

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5

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23 January 2020

author name string

Jang Choon Lee

1

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23 January 2020

Kwang Seok Ahn

2

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23 January 2020

Soo-Jin Jeong

3

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23 January 2020

Ji Hoon Jung

4

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23 January 2020

Yun-Hee Rhee

6

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23 January 2020

Sun-Hee Kim

7

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23 January 2020

Si-Young Kim

8

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23 January 2020

Hwi-Joong Yoon

9

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23 January 2020

Shudong Zhu

10

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23 January 2020

Chang-Yan Chen

11

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23 January 2020

Sung-Hoon Kim

12

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23 January 2020

language of work or name

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1 June 2011

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Journal of Cellular Biochemistry

23 January 2020

published in

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23 January 2020

volume

112

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23 January 2020

page(s)

1552-1562

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23 January 2020

issue

6

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Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution

23 January 2020

cites work

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Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1.

21 January 2018

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Recent major improvement in long-term survival of younger patients with multiple myeloma.

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Stats: multifaceted regulators of transcription

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

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Proteasome inhibitor bortezomib for the treatment of multiple myeloma.

21 January 2018

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Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

21 January 2018

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Multiple myeloma: management of adverse events

21 January 2018

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Diagnosis and management of multiple myeloma

21 January 2018

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Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell lymphoma

21 January 2018

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Mixed lineage kinase 3 connects reactive oxygen species to c-Jun NH2-terminal kinase-induced mitochondrial apoptosis in genipin-treated PC3 human prostate cancer cells

21 January 2018

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STATs: signal transducers and activators of transcription

21 January 2018

1 reference

SHP-1 exhibits a pro-apoptotic function in antigen-stimulated mast cells: positive regulation of mitochondrial death pathways and negative regulation of survival signaling pathways

21 January 2018

1 reference

γ-Tocotrienol but not γ-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents

21 January 2018

1 reference

Genipin-induced apoptosis in hepatoma cells is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of mitochondrial pathway

21 January 2018

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Src kinases as therapeutic targets for cancer

21 January 2018

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Anti-inflammatory evaluation of gardenia extract, geniposide and genipin

21 January 2018

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Genipin enhances the mechanical properties of tissue-engineered cartilage and protects against inflammatory degradation when used as a medium supplement

21 January 2018

1 reference

Baicalein, a component of Scutellaria radix from Huang-Lian-Jie-Du-Tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells.

21 January 2018

1 reference

Aplidin, a marine organism-derived compound with potent antimyeloma activity in vitro and in vivo

21 January 2018

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Genipin inhibits the inflammatory response of rat brain microglial cells.

21 January 2018

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Paclitaxel downregulates tissue factor in cancer and host tumour-associated cells

21 January 2018

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Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA double-strand breaks.

21 January 2018

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Butein suppresses constitutive and inducible signal transducer and activator of transcription (STAT) 3 activation and STAT3-regulated gene products through the induction of a protein tyrosine phosphatase SHP-1.

21 January 2018

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Curcumin in combination with bortezomib synergistically induced apoptosis in human multiple myeloma U266 cells

21 January 2018

1 reference

5-hydroxy-2-methyl-1,4-naphthoquinone, a vitamin K3 analogue, suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase, SHP-1: potential role in chemosensitization

21 January 2018

1 reference

A common signaling cascade may underlie "addiction" to the Src, BCR-ABL, and EGF receptor oncogenes

21 January 2018

1 reference

A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma

21 January 2018

1 reference

Src kinase activity is regulated by the SHP-1 protein-tyrosine phosphatase

21 January 2018

1 reference

Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3.

21 January 2018

1 reference

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

21 January 2018

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The STATs of cancer--new molecular targets come of age

21 January 2018

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Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets

21 January 2018

1 reference

Three new monoterpenoids from the fruit of Genipa americana

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/CPB.55.632

Identifiers

DOI

10.1002/JCB.23077

1 reference

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23 January 2020

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