Downregulation of mitochondrial lon protease impairs mitochondrial function and causes hepatic insulin resistance in human liver SK-HEP-1 cells. (Q39586726)

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scientific article published on 24 February 2011

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English	Downregulation of mitochondrial lon protease impairs mitochondrial function and causes hepatic insulin resistance in human liver SK-HEP-1 cells.	scientific article published on 24 February 2011

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23 January 2020

Downregulation of mitochondrial lon protease impairs mitochondrial function and causes hepatic insulin resistance in human liver SK-HEP-1 cells (English)

1 reference

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23 January 2020

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insulin resistance

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6

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23 January 2020

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H J Lee

1

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23 January 2020

K Chung

2

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23 January 2020

H Lee

3

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23 January 2020

K Lee

4

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23 January 2020

J H Lim

5

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23 January 2020

publication date

24 February 2011

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23 January 2020

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23 January 2020

54

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23 January 2020

6

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23 January 2020

1437-1446

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23 January 2020

https://scigraph.springernature.com/pub.10.1007/s00125-011-2074-z

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Mitochondrial dysfunction and type 2 diabetes

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21 January 2018

The role of mitochondria in health and disease

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Integrative analysis of the mitochondrial proteome in yeast

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Mitochondrial protein homeostasis: the cooperative roles of chaperones and proteases

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21 January 2018

Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism

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21 January 2018

Mitochondrial protein oxidation and degradation in response to oxidative stress and aging

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21 January 2018

Protein degradation within mitochondria: versatile activities of AAA proteases and other peptidases

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21 January 2018

Cleavage site selection within a folded substrate by the ATP-dependent lon protease

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21 January 2018

Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance

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21 January 2018

Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease

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21 January 2018

Importance of the lon protease in mitochondrial maintenance and the significance of declining lon in aging.

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Requirement for the yeast gene LON in intramitochondrial proteolysis and maintenance of respiration.

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21 January 2018

Enhanced mitochondrial biogenesis is associated with increased expression of the mitochondrial ATP-dependent Lon protease

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21 January 2018

Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death

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21 January 2018

Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1.

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21 January 2018

Coupling mitochondrial dysfunction to endoplasmic reticulum stress response: a molecular mechanism leading to hepatic insulin resistance

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21 January 2018

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

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21 January 2018

Palmitate attenuates insulin signaling and induces endoplasmic reticulum stress and apoptosis in hypothalamic neurons: rescue of resistance and apoptosis through adenosine 5' monophosphate-activated protein kinase activation

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21 January 2018

Lipid-induced ER stress: synergistic effects of sterols and saturated fatty acids

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21 January 2018

Banting Lecture 1997. Control of glucose uptake and release by the liver in vivo

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21 January 2018

Mitochondrial dysfunction induces triglyceride accumulation in 3T3-L1 cells: role of fatty acid beta-oxidation and glucose

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21 January 2018

Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

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21 January 2018

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

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21 January 2018

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

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21 January 2018

A mitochondrial specific stress response in mammalian cells

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21 January 2018

Mitochondrial protein quality control: implications in ageing

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21 January 2018

Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity

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21 January 2018

Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress.

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21 January 2018

Gene expression profile of aging and its retardation by caloric restriction

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21 January 2018

Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix

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21 January 2018

Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL.

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21 January 2018

Overproduction of the Lon protease triggers inhibition of translation in Escherichia coli: involvement of the yefM-yoeB toxin-antitoxin system

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21 January 2018

Mitochondrial dysfunction induces aberrant insulin signalling and glucose utilisation in murine C2C12 myotube cells

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21 January 2018

Insulin stimulates liver glucose uptake in humans: an 18F-FDG PET Study.

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12 December 2020

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