Legalon-SIL downregulates HCV core and NS5A in human hepatocytes expressing full-length HCV. (Q39560356)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21483629%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Legalon-SIL downregulates HCV core and NS5A in human hepatocytes expressing full-length HCV (English)

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28 January 2020

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2

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28 January 2020

author name string

Marjan Mehrab-Mohseni

1

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28 January 2020

Nury Steuerwald

3

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28 January 2020

Sriparna Ghosh

4

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28 January 2020

Laura W Schrum

5

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28 January 2020

Herbert L Bonkovsky

6

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28 January 2020

language of work or name

English

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publication date

1 April 2011

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World Journal of Gastroenterology

28 January 2020

published in

1 reference

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28 January 2020

volume

17

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28 January 2020

issue

13

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28 January 2020

page(s)

1694-1700

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Identification of hepatoprotective flavonolignans from silymarin

28 January 2020

cites work

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14 September 2017

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14 September 2017

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Inhibition of T-cell inflammatory cytokines, hepatocyte NF-kappaB signaling, and HCV infection by standardized Silymarin

14 September 2017

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14 September 2017

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Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose

14 September 2017

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14 September 2017

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Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B.

14 September 2017

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Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group

14 September 2017

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

14 September 2017

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The world according to Maf

14 September 2017

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The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase

14 September 2017

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Effects of silymarin on hepatitis C virus and haem oxygenase-1 gene expression in human hepatoma cells

14 September 2017

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HCV proteins increase expression of heme oxygenase-1 (HO-1) and decrease expression of Bach1 in human hepatoma cells

14 September 2017

1 reference

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Hepatitis C virus-core and non structural proteins lead to different effects on cellular antioxidant defenses

14 September 2017

1 reference

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Microsomal heme oxygenase. Characterization of the enzyme

14 September 2017

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Silibinin is a potent antiviral agent in patients with chronic hepatitis C not responding to pegylated interferon/ribavirin therapy.

15 June 2018

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Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial.

21 August 2018

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Silibinin polarizes Th1/Th2 immune responses through the inhibition of immunostimulatory function of dendritic cells.

21 August 2018

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Effects of Silybum marianum on serum hepatitis C virus RNA, alanine aminotransferase levels and well-being in patients with chronic hepatitis C.

21 August 2018

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Silymarin suppresses TNF-induced activation of NF-kappa B, c-Jun N-terminal kinase, and apoptosis.

21 August 2018

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Scavenging of reactive oxygen species and inhibition of arachidonic acid metabolism by silibinin in human cells

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21483629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of Bach1 and Nrf2 in up-regulation of the heme oxygenase-1 gene by cobalt protoporphyrin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21483629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21483629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3748/WJG.V17.I13.1694

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21483629%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

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28 January 2020

PubMed publication ID

21483629

1 reference