TP53 mutations in newly diagnosed acute myeloid leukemia: Clinicomolecular characteristics, response to therapy, and outcomes (Q39555179)

19 June 2018

title

TP53 mutations in newly diagnosed acute myeloid leukemia: Clinicomolecular characteristics, response to therapy, and outcomes (English)

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19 June 2018

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acute myeloid leukemia

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2

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19 June 2018

Hagop Kantarjian

17

Hagop M Kantarjian

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19 June 2018

15

Zeev Estrov

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19 June 2018

16

Jorge Cortes

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19 June 2018

7

Gautam Borthakur

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19 June 2018

3

Farhad Ravandi

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19 June 2018

8

Elias Jabbour

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19 June 2018

12

Sherry Pierce

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19 June 2018

PMCID

5269552

Guillermo Garcia-Manero

4

Guillermo Garcia-Manero

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19 June 2018

9

Marina Konopleva

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19 June 2018

1

Tapan M Kadia

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19 June 2018

Naval Daver

10

Naval G Daver

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19 June 2018

Courtney D DiNardo

11

Courtney Dinardo

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19 June 2018

Michael Andreef

5

Michael Andreef

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19 June 2018

Rashmi Kanagal-shamanna

13

Rashmi Kanagal-Shamanna

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19 June 2018

Koichi Takahashi

6

Koichi Takahashi

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19 June 2018

Keyur P Patel

14

Keyur Patel

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19 June 2018

language of work or name

English

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publication date

26 July 2016

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19 June 2018

published in

Cancer

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19 June 2018

TP53 mutation in patients with high-risk acute myeloid leukaemia treated with allogeneic haematopoietic stem cell transplantation

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22 June 2018

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TP53 mutations in de novo acute myeloid leukemia patients: longitudinal follow-ups show the mutation is stable during disease evolution.

22 June 2018

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Mutational profiling of therapy-related myelodysplastic syndromes and acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases

22 June 2018

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Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.

22 June 2018

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Immunotherapeutic strategies for relapse control in acute myeloid leukemia

22 June 2018

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Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

22 June 2018

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Acquired genomic copy number aberrations and survival in adult acute myelogenous leukemia

22 June 2018

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TP53 mutations in human cancers: origins, consequences, and clinical use

22 June 2018

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Mouse models of human AML accurately predict chemotherapy response

22 June 2018

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The prognostic impact of 17p (p53) deletion in 2272 adults with acute myeloid leukemia

22 June 2018

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Genetics of therapy-related myelodysplasia and acute myeloid leukemia

22 June 2018

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p53 mutation heterogeneity in cancer

22 June 2018

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Acute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile

22 June 2018

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Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.

22 June 2018

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

22 June 2018

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Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice.

22 June 2018

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Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia.

21 August 2018

1 reference

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TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis.

21 August 2018

1 reference

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Chromosomal aberrations in 17p predict in vitro drug resistance and short overall survival in acute myeloid leukemia.

21 August 2018

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p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.

21 August 2018

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FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia.

21 August 2018

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Mutant p53 protein expression interferes with p53-independent apoptotic pathways.

21 August 2018

1 reference

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TP53 mutations in older adults with acute myeloid leukemia.

21 August 2018

1 reference

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TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome

1 October 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.30203

7 January 2021

Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.30203

7 January 2021

Prognostic value of p53 gene mutations and the product expression in de novo acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.30203

7 January 2021

Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor progno

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.30203

7 January 2021

Cytogenetic findings in blastoid mantle cell lymphoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.30203

7 January 2021

Identifiers

DOI

10.1002/CNCR.30203

1 reference

19 June 2018

PMCID

5269552

1 reference

19 June 2018

PubMed ID

27463065

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19 June 2018