Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma (Q39530717)

6 October 2017

Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma (English)

1 reference

6 October 2017

1 reference

1

1 reference

12 September 2017

37

1 reference

12 September 2017

18

Laura J Hardie

0 references

Puya Gharahkhani

Puya Gharahkhani

7

0 references

Hans Prenen

Hans Prenen

25

0 references

Stuart Macgregor

Stuart MacGregor

38

0 references

Geoffrey Liu

Geoffrey Liu

20

0 references

Janusz A. Jankowski

Janusz Jankowski

36

0 references

Leslie Bernstein

15

Leslie Bernstein

1 reference

6 October 2017

Claire Palles

8

0 references

Qianchuan He

Qianchuan He

2

0 references

Nicholas J. Shaheen

14

Nicholas J Shaheen

1 reference

6 October 2017

9

Jesper Lagergren

1 reference

6 October 2017

29

Paul Moayyedi

1 reference

6 October 2017

12

Carlos Caldas

1 reference

6 October 2017

19

Paul D Pharoah

1 reference

6 October 2017

35

Ian Tomlinson

1 reference

6 October 2017

22

Douglas A Corley

1 reference

6 October 2017

16

Marilie D Gammon

1 reference

6 October 2017

17

Anna H Wu

1 reference

6 October 2017

26

Laura Chegwidden

1 reference

6 October 2017

Lisa G Johnson

3

1 reference

6 October 2017

Lynn Onstad

4

1 reference

6 October 2017

David M Levine

5

1 reference

6 October 2017

Aaron P Thrift

6

1 reference

6 October 2017

Rebecca C Fitzgerald

10

1 reference

6 October 2017

Weimin Ye

11

1 reference

6 October 2017

Nigel C Bird

13

1 reference

6 October 2017

Prassad Iyer

21

1 reference

6 October 2017

Harvey A Risch

23

1 reference

6 October 2017

Wong-Ho Chow

24

1 reference

6 October 2017

Sharon Love

27

1 reference

6 October 2017

Stephen Attwood

28

1 reference

6 October 2017

David MacDonald

30

1 reference

6 October 2017

Rebecca Harrison

31

1 reference

6 October 2017

Peter Watson

32

1 reference

6 October 2017

Hugh Barr

33

1 reference

6 October 2017

John deCaestecker

34

1 reference

6 October 2017

Thomas L Vaughan

39

1 reference

6 October 2017

Margaret M Madeleine

40

1 reference

6 October 2017

language of work or name

English

0 references

publication date

2 August 2016

1 reference

6 October 2017

1 reference

6 October 2017

66

1 reference

6 October 2017

10

1 reference

6 October 2017

1739-1747

1 reference

Supportive evidence for FOXP1, BARX1, and FOXF1 as genetic risk loci for the development of esophageal adenocarcinoma

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Adiposity and cancer risk: new mechanistic insights from epidemiology

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Precision prevention of oesophageal adenocarcinoma

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Pathway-based analysis tools for complex diseases: a review

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Integrative post-genome-wide association analysis of CDKN2A and TP53 SNPs and risk of esophageal adenocarcinoma

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Cigarette smoking and variations in systemic immune and inflammation markers

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Reflux composition influences the level of NF-κB activation and upstream kinase preference in oesophageal adenocarcinoma cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Inflammation amplifier, a new paradigm in cancer biology

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Yin and yang of tumor inflammation: how innate immune suppressors shape the tumor microenvironments

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Germline genetic contributions to risk for esophageal adenocarcinoma, Barrett's esophagus, and gastroesophageal reflux

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Bile acids increase levels of microRNAs 221 and 222, leading to degradation of CDX2 during esophageal carcinogenesis.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Meta-analysis methods for genome-wide association studies and beyond

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Inflammation and Barrett's carcinogenesis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Cellular origin of Barrett's esophagus: controversy and therapeutic implications

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Total and abdominal adiposity are associated with inflammation in older adults using a factor analysis approach

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Use of statin medications and risk of esophageal adenocarcinoma in persons with Barrett's esophagus

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

A linear complexity phasing method for thousands of genomes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Nonsteroidal anti-inflammatory drug use reduces risk of adenocarcinomas of the esophagus and esophagogastric junction in a pooled analysis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Genome-wide association study identifies novel loci predisposing to cutaneous melanoma

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Hallmarks of Cancer: The Next Generation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Impact of smoking on inflammation: overview of molecular mechanisms.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

The NIH Roadmap Epigenomics Mapping Consortium

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Multiple roles of microsomal glutathione transferase 1 in cellular protection: a mechanistic study

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Quality control and quality assurance in genotypic data for genome-wide association studies

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

LocusZoom: regional visualization of genome-wide association scan results

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno- or squamous cell carcinoma

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Chronic inflammation: a common and important factor in the pathogenesis of neoplasia

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Non-steroidal anti-inflammatory drugs and risk of neoplastic progression in Barrett's oesophagus: a prospective study

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Proinflammatory cytokine and nuclear factor kappa-B expression along the inflammation-metaplasia-dysplasia-adenocarcinoma sequence in the esophagus

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Effect of inflammation on cyclooxygenase (COX)-2 expression in benign and malignant oesophageal cells.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Analysis of the glutathione S-transferase (GST) gene family

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Activation of NFkappaB represents the central event in the neoplastic progression associated with Barrett's esophagus: a possible link to the inflammation and overexpression of COX-2, PPARgamma and growth factors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

17 June 2018

Inflammation and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Structural organization of the microsomal glutathione S-transferase gene (MGST1) on chromosome 12p13.1-13.2. Identification of the correct promoter region and demonstration of transcriptional regulation in response to oxidative stress

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Body mass index and risk of adenocarcinomas of the esophagus and gastric cardia

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Inflammation, chromosomal instability, and cancer: the schistosomiasis model.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

The incidence of esophageal adenocarcinoma continues to rise: analysis of period and birth cohort effects on recent trends

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Tumour necrosis factor-alpha in Barrett's oesophagus: a potential novel mechanism of action.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Circulating tumor necrosis factor alpha concentrations are higher in abdominal versus peripheral obesity.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Obesity, alcohol, and tobacco as risk factors for cancers of the esophagus and gastric cardia: adenocarcinoma versus squamous cell carcinoma.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

Symptomatic Gastroesophageal Reflux as a Risk Factor for Esophageal Adenocarcinoma

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296402

COX-2 CA-haplotype is a risk factor for the development of esophageal adenocarcinoma

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27486097

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Microsomal glutathione S-transferase gene polymorphisms and colorectal cancer risk in a Han Chinese population

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27486097

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Arterial stiffening and systemic endothelial activation induced by smoking: The role of COX-1 and COX-2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27486097

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1136/GUTJNL-2016-311622

1 reference

10.1136/GUTJNL-2016-311622

6 October 2017

0 references

Dimensions Publication ID

0 references

1 reference

6 October 2017

1 reference