Lupeol, a novel androgen receptor inhibitor: implications in prostate cancer therapy. (Q39516408)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712449%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Lupeol, a novel androgen receptor inhibitor: implications in prostate cancer therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712449%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

ChEBI release 2020-05-28

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712449%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Mohammad Saleem

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712449%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

author name string

Shrawan Kumar Mishra

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712449%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

R Jeffery Karnes

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712449%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

language of work or name

English

0 references

publication date

28 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712449%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

published in

Clinical Cancer Research

1 reference

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6 February 2020

volume

17

1 reference

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6 February 2020

issue

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712449%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

page(s)

5379-5391

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712449%20AND%20SRC:MED&resulttype=core&format=json

New strategies in metastatic prostate cancer: targeting the androgen receptor signaling pathway

6 February 2020

cites work

1 reference

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12 September 2017

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12 September 2017

1 reference

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12 September 2017

1 reference

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MRI for men undergoing active surveillance or with rising PSA and negative biopsies

12 September 2017

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12 September 2017

1 reference

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Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination

12 September 2017

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CYP17 inhibition as a hormonal strategy for prostate cancer.

12 September 2017

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Androgen receptor structural and functional elements: role and regulation in prostate cancer

12 September 2017

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Multifaceted interaction between the androgen and Wnt signaling pathways and the implication for prostate cancer

12 September 2017

1 reference

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Androgen receptor action in hormone-dependent and recurrent prostate cancer.

12 September 2017

1 reference

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Androgen receptor in prostate cancer

12 September 2017

1 reference

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Androgen-induced recruitment of RNA polymerase II to a nuclear receptor-p160 coactivator complex

12 September 2017

1 reference

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Beta-catenin binds to the activation function 2 region of the androgen receptor and modulates the effects of the N-terminal domain and TIF2 on ligand-dependent transcription

12 September 2017

1 reference

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Bone metastatic LNCaP-derivative C4-2B prostate cancer cell line mineralizes in vitro

12 September 2017

1 reference

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The control of prostate-specific antigen expression and gene regulation by pharmacological agents.

12 September 2017

1 reference

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Nuclear receptor coregulators: cellular and molecular biology

12 September 2017

1 reference

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Intragenic rearrangement and altered RNA splicing of the androgen receptor in a cell-based model of prostate cancer progression

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4573593

Androgens activate mitogen-activated protein kinase via epidermal growth factor receptor/insulin-like growth factor 1 receptor in the mouse PC-1 cell line

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4573593

Aberrant activation of the androgen receptor by NF-kappaB2/p52 in prostate cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4573593

Prolonged treatment with bicalutamide induces androgen receptor overexpression and androgen hypersensitivity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4573593

Design and synthesis of androgen receptor antagonists with bulky side chains for overcoming antiandrogen resistance

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4573593

Suppression of cFLIP by lupeol, a dietary triterpene, is sufficient to overcome resistance to TRAIL-mediated apoptosis in chemoresistant human pancreatic cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4573593

Bicalutamide failure in prostate cancer treatment: involvement of Multi Drug Resistance proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4573593

A novel dietary triterpene Lupeol induces fas-mediated apoptotic death of androgen-sensitive prostate cancer cells and inhibits tumor growth in a xenograft model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4573593

Androgen receptor-dependent PSA expression in androgen-independent prostate cancer cells does not involve androgen receptor occupancy of the PSA locus

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4573593

Effects of WNT/beta-catenin pathway activation on signaling through T-cell factor and androgen receptor in prostate cancer cell lines.

14 September 2017

1 reference

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Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor.

14 September 2017

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Mechanism of antiandrogen action: key role of hsp90 in conformational change and transcriptional activity of the androgen receptor

14 September 2017

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Lupeol inhibits proliferation of human prostate cancer cells by targeting beta-catenin signaling

25 September 2017

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PSA and beyond: the past, present, and future of investigative biomarkers for prostate cancer.

17 June 2018

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Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors.

21 August 2018

1 reference

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Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway.

21 August 2018

1 reference

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Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation

21 August 2018

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Androgen receptor mutations in androgen-independent prostate cancer: Cancer and Leukemia Group B Study 9663.

21 August 2018

1 reference

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Androgen receptor mutations in prostate cancer.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4573593

Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21712449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pharmacokinetics and tissue distribution of betulinic acid in CD-1 mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21712449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Collocation of androgen receptor gene mutations in prostate cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21712449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1078-0432.CCR-11-0916

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712449%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712449%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference