The metabolism and mechanism of action of 1,25-dihydroxyvitamin D3. (Q39507418)

12 September 2017

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title

The metabolism and mechanism of action of 1,25-dihydroxyvitamin D3. (English)

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12 September 2017

R Kumar

1

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12 September 2017

language of work or name

English

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publication date

1 December 1986

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12 September 2017

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12 September 2017

30

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12 September 2017

6

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12 September 2017

793-803

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https://scigraph.springernature.com/pub.10.1038/ki.1986.258

12 September 2017

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cites work

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Photosynthesis of Previtamin D 3 in Human Skin and the Physiologic Consequences

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7 January 2021

Increased skin pigment reduces the capacity of skin to synthesise vitamin D3.

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7 January 2021

Spectral character of sunlight modulates photosynthesis of previtamin D3 and its photoisomers in human skin

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7 January 2021

Lymphatic absorption and transport of retinol and vitamin D-3 from rat intestine Evidence for different pathways

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7 January 2021

A method for studying plasma transport of vitamin D applicable to hypervitaminosis D

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7 January 2021

Serum protein binding of 1,25-dihydroxyvitamin D: a reevaluation by direct measurement of free metabolite levels.

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https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

The role of the liver in the metabolism of vitamin D.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

The effect of hepatectomy on the synthesis of 25-hydroxyvitamin D3

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https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Subcellular location of rat liver calciferol-25-hydroxylase

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Resolution and reconstitution of soluble components of rat liver microsomal vitamin D3-25-hydroxylase.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Evidence that 1,25-dihydroxyvitamin D3 inhibits the hepatic production of 25-hydroxyvitamin D in man

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Orthophosphate therapy decreases urinary calcium excretion and serum 1,25-dihydroxyvitamin D concentrations in idiopathic hypercalciuria

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https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Synthesis and biologic activity of a C-ring analogue of vitamin D3: biologic and protein binding properties of 11 alpha-hydroxyvitamin D3

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https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Serum vitamin D-binding protein is a third member of the albumin and alpha fetoprotein gene family

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Influence of the vitamin D-binding protein on the serum concentration of 1,25-dihydroxyvitamin D3. Significance of the free 1,25-dihydroxyvitamin D3 concentration

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Isolation and identification of 1,25-dihydroxycholecalciferol. A metabolite of vitamin D active in intestine

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

A rapidly acting metabolite of vitamin D3.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

1,25-dihydroxycholecalciferol: identification of the proposed active form of vitamin D3 in the intestine

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Identification of 1,25-Dihydroxycholecalciferol, a New Kidney Hormone controlling Calcium Metabolism

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https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Unique Biosynthesis by Kidney of a Biologically Active Vitamin D Metabolite

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Localization of 25-hydroxyvitamin D3-lα-hydroxylase activity in the mammalian kidney

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Site of 1,25(OH)2 vitamin D3 synthesis in the kidney

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Localization of 25-hydroxyvitamin D3 1 alpha-hydroxylase and 24-hydroxylase along the rat nephron

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

25-Hydroxycholecalciferol-1-hydroxylase: a specific requirement for NADPH and a hemoprotein component in chick kidney mitochondria.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Purification and properties of chick renal mitochondrial ferredoxin

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Renal mitochondrial ferredoxin active in 25-hydroxyvitamin D3 1.alpha.-hydroxylase. Characterization of the iron-sulfur cluster using interprotein cluster transfer and electron paramagnetic resonance spectroscopy

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Bovine renal mitochondrial vitamin D3 hydroxylases: regulation of in vitro activities by inhibitors and antioxidants

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Metabolism of 1,25-dihydroxyvitamin D3

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Infusions of parathyroid hormone in ruminants: hypercalcemia and reduced plasma 1,25-dihydroxyvitamin D concentrations

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Metabolism of 1,25-dihydroxycholecalciferol in the rat

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

The Stimulation of 1,25-Dihydroxycholecalciferol Metabolism in Vitamin D-deficient Rats by 1,25-Dihydroxycholecalciferol Treatment

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Metabolism and Excretion of3H-1,2 5-(OH)2-Vitamin D3in Healthy Adults*

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Production, degradation, and circulating levels of 1,25-dihydroxyvitamin D in health and in chronic glucocorticoid excess

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Side chain metabolism of 25-hydroxy-[26,27-14C] vitamin D3 and 1,25-dihydroxy-[26,27-14C] vitamin D3 in vivo

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Metabolism of 1,25-dihydroxyvitamin D3: evidence for side-chain oxidation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Isolation and characterization of 1.alpha.-hydroxy-23-carboxytetranorvitamin D: a major metabolite of 1,25-dihydroxyvitamin D3

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Calcitroic acid: biological activity and tissue distribution studies.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

1,24,25-Trihydroxyvitamin D3: a circulating metabolite in vitamin D2-treated bovine

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Effect of dietary calcium and phosphorus on intestinal calcium absorption and vitamin D metabolism

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Isolation of a new metabolite of vitamin D produced in vivo, 1α,25-dihydroxyvitamin D3-26,23-lactone

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Enterohepatic physiology of 1,25-dihydroxyvitamin D3

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Hepatic and Intestinal Osteodystrophy and the Hepatobiliary Metabolism of Vitamin D

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Synthesis and biological activity of vitamin D2 3 beta-glucosiduronate and vitamin D2 3 beta-sulfate: role of vitamin D2 conjugates in calcium homeostasis

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https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Role of vitamin D glucosiduronate in calcium homeostasis

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https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

1,25,26-trihydroxyvitamin D3: isolation, identification, and biological activity

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

1 Alpha-25,26-trihydroxyvitamin D3: an in vivo and in vitro metabolite of vitamin D3

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https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Enterohepatic circulation of vitamin D: a reappraisal of the hypothesis

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Elevated production rate of 1,25-dihydroxyvitamin D in patients with absorptive hypercalciuria

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Impaired vitamin D metabolism with aging in women. Possible role in pathogenesis of senile osteoporosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Influence of sodium on calcium transport by the rat small intestine

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

1,25-Dihydroxycholecalciferol: Inhibition of Action in Organ-cultured Intestine by Actinomycin D and α-Amanitin

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Intestinal calcium transport: evidence for two distinct mechanisms of action of 1,25-dihydroxyvitamin D3

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Relationship of intestinal and plasma calcium-binding protein to intestinal calcium absorption

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Calcium-ion-binding activity in human small-intestinal mucosal cytosol. Purification of two proteins and interrelationship of calcium-binding fractions

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Ca2+-binding protein from human kidney. Purification and properties

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

The amino acid sequence of porcine intestinal calcium-binding protein

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Ornithine decarboxylase activity in chick duodenum induced by 1 alpha, 25-dihydroxycholecalciferol

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Distribution of ornithine decarboxylase activity induced by 1 alpha,25-dihydroxyvitamin D3 in chick duodenal villus mucosa

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Effect of 1,25-dihydroxyvitamin D on S-adenosylmethionine decarboxylase in chick intestine

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Evidence for a 1,25-dihydroxycholecalciferol-dependent spermine-binding protein in chick duodenal mucosa

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Intestinal 1, 25-dihydroxyvitamin D3 receptors: Hormone-dependent uptake and saturability of nuclear components in vitro

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Rapid Enhancement of Chick Intestinal DNA-Dependent RNA Polymerase II Activity by 1α,25-Dihydroxyvitamin D 3 , In Vivo

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Stimulation of intestinal calcium-binding-protein mRNA synthesis in the nucleus of vitamin D-deficient chicks by 1,25-dihydroxycholecalciferol

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Purification of chicken intestinal receptor for 1,25-dihydroxyvitamin D

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Development of hybridomas secreting monoclonal antibodies to the chicken intestinal 1 alpha,25-dihydroxyvitamin D3 receptor

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Purification of chicken intestinal receptor for 1 alpha, 25-dihydroxyvitamin D3 to apparent homogeneity

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Development of a radioligand immunoassay for 1,25-dihydroxycholecalciferol receptors utilizing monoclonal antibody

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Vitamin D 3 —Resistant Fibroblasts Have Immunoassayable 1,25-Dihydroxyvitamin D 3 Receptors

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Evidence for a reactive sulfhydryl in the DNA binding domain of the 1,25-dihydroxyvitamin D3 receptor

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Intestinal 1,25-dihydroxyvitamin D3 binding protein: specificity of binding

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Calcium translocation by Golgi and lateral-basal membrane vesicles from rat intestine: decrease in vitamin D-deficient rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Embryonic chick intestine in organ culture: interaction of adenylate cyclase system and vitamin D3-mediated calcium absorptive mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Early rise in cyclic GMP after 1,25-dihydroxycholecalciferol administration in the chick intestinal mucosa

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Studies on the mechanism of action of calciferol. V. Turnover time of chick intestinal epithelial cells in relation to the intestinal action of vitamin D.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

A morphometric investigation of the duodenal mucosa of normal, vitamin D-deficient, and vitamin D-replete rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Lysosomal proliferation in rachitic avian intestinal absorptive cells following 1,25-dihydroxycholecalciferol

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

1,25-Dihydroxyvitamin D3 rapidly alters the morphology of the duodenal mucosa of rachitic chicks: evidence for novel effects of 1,25-dihydroxyvitamin D3

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Calcium uptake in isolated brush-border vesicles from rat small intestine

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

1,25-dihydroxyvitamin D3 increases the activity of the intestinal phosphatidylcholine deacylation-reacylation cycle

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Evidence for multiple effects of vitamin D3 on calcium absorption: response of rachitic chicks, with or without partial vitamin D3 repletion, to 1,25-dihydroxyvitamin D3.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Vitamin D-mediated intestinal calcium transport. Effects of essential fatty acid deficiency and spin label studies of enterocyte membrane lipid fluidity

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Vitamin D-dependent phosphorylation of an intestinal protein

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Phosphorylated intermediates of Ca2+ -ATPase and alkaline phosphatase in plasma membranes from rat duodenal epithelium

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

1,25-Dihydroxyvitamin D stimulation of specific membrane proteins in chick intestine

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Vitamin D and intestinal cell membranes

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Incorporation of [3H]leucine into an actin-like protein in response to 1,25-dihydroxycholecalciferol in chick intestinal brush borders

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Vitamin D stimulated, calcium-dependent adenosine triphosphatase from brush borders of rat small intestine

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Differentiation of the changes in alkaline phosphatase from calcium ion-activated adenosine triphosphatase activities associated with increased calcium absorption in chick intestine

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Vitamin D stimulation of calcium-dependent adenosine triphosphatase in chick intestinal brush borders.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

1α,25-dihydroxy-vitamin D-3 regulates ATP-dependent calcium transport in basolateral plasma membranes of rat enterocytes

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Decreased intestinal calcium absorption in vivo and normal brush border membrane vesicle calcium uptake in cortisol-treated chickens: evidence for dissociation of calcium absorption from brush border vesicle uptake

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Renal actions of vitamin D in D-deficient rats.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Evidence for a direct action of cholecalciferol and 25-hydroxycholecalciferol on the renal transport of phosphate, sodium, and calcium

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

The acute effect of 25-hydroxycholecalciferol on renal handling of phosphorus. Evidence for a parathyroid hormone-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Parathyroid hormone and 25-hydroxy vitamin D3: synergistic and antagonistic effects on renal phosphate transport

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

The Acute Renal Tubular Effects of 1,25-Dihydroxycholecalciferol

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Effects of vitamin D on renal handling of calcium, magnesium and phosphate in the hamster

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Effect of 1,25-dihydroxyvitamin D3 on the renal handling of Pi in thyroparathyroidectomized rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Resistance to the phosphaturic and calcemic actions of parathyroid hormone during phosphate depletion. Prevention by 1,25-dihydroxyvitamin D3.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

1,25 Dihydroxy-vitamin D3 in normal man and patients with renal failure

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Mechanism of stimulation of renal phosphate transport by 1,25-dihydroxycholecalciferol

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Target cells for 1,25-dihydroxyvitamin D3 in intestinal tract, stomach, kidney, skin, pituitary, and parathyroid

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Vitamin D3-induced calcium-binding protein: partial purification, electrophoretic visualization, and tissue distribution.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Vitamin D--dependent calcium binding protein: immunocytochemical localization in chick kidney

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

The amino acid sequence of the NH2-terminal portion of rat and human vitamin D binding protein: evidence for a high degree of homology between rat and human vitamin D binding protein

1 reference

https://api.crossref.org/works/10.1038%2FKI.1986.258

7 January 2021

Identifiers

DOI

10.1038/KI.1986.258

1 reference

Dimensions Publication ID

12 September 2017

1002458094

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Fatcat ID

release_gqpy5ppvvzaw5ml4anbv4cu47u

0 references

1 reference