Benzodiazepine modulation of GABA(A) receptor opening frequency depends on activation context: a patch clamp and simulation study. (Q39487367)

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28 January 2020

title

Benzodiazepine modulation of GABA(A) receptor opening frequency depends on activation context: a patch clamp and simulation study (English)

1 reference

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28 January 2020

author

Andre Hollis Lagrange

3

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28 January 2020

author name string

Matt T Bianchi

1

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28 January 2020

Emmanuel J Botzolakis

2

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28 January 2020

Robert L Macdonald

4

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publication date

15 May 2009

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28 January 2020

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28 January 2020

volume

85

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28 January 2020

issue

2-3

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28 January 2020

page(s)

212-220

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Activation of GABAA receptors: views from outside the synaptic cleft.

28 January 2020

cites work

1 reference

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Enhanced macroscopic desensitization shapes the response of alpha4 subtype-containing GABAA receptors to synaptic and extrasynaptic GABA

12 September 2017

1 reference

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Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors

12 September 2017

1 reference

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Presynaptic, extrasynaptic and axonal GABAA receptors in the CNS: where and why?

12 September 2017

1 reference

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Effect of zolpidem on miniature IPSCs and occupancy of postsynaptic GABAA receptors in central synapses

12 September 2017

1 reference

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On the stochastic properties of bursts of single ion channel openings and of clusters of bursts

12 September 2017

1 reference

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Interaction of benzodiazepines with central nervous glycine receptors: possible mechanism of action

12 September 2017

1 reference

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Differential regulation of gamma-aminobutyric acid receptor channels by diazepam and phenobarbital

12 September 2017

1 reference

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Chlordiazepoxide selectively augments GABA action in spinal cord cell cultures

12 September 2017

1 reference

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Modifications of a commercial perfusion system for use in ultrafast solution exchange during patch clamp recording

12 September 2017

1 reference

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Selective modulation of tonic and phasic inhibitions in dentate gyrus granule cells

14 September 2017

1 reference

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Agonist Trapping by GABAA Receptor Channels.

14 September 2017

1 reference

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Which GABAA-receptor subtypes really occur in the brain?

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

The impact of receptor desensitization on fast synaptic transmission

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

Direct evidence for diazepam modulation of GABAA receptor microscopic affinity.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in culture

15 June 2018

1 reference

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Neher and Sakmann win Nobel Prize for patch-clamp work

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

Diazepam and chlordiazepoxide: powerful GABA antagonists in explants of rat cerebellum

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

Benzodiazepines specifically modulate GABA-mediated postsynaptic inhibition in cultured mammalian neurones

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

Which GABA(A) receptor subunits are necessary for tonic inhibition in the hippocampus?

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABAA receptor desensitization and deactivation.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

Two different mechanisms of disinhibition produced by GABAA receptor mutations linked to epilepsy in humans.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

Benzodiazepines do not modulate desensitization of recombinant alpha1beta2gamma2 GABA(A) receptors.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

Modulation of synaptic GABAA receptor function by benzodiazepines in area CA3 of rat hippocampal slice cultures.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

Desensitized states prolong GABAA channel responses to brief agonist pulses.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

Benzodiazepine and beta-carboline regulation of single GABAA receptor channels of mouse spinal neurones in culture.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834588

GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19447010

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An update on GABAA receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19447010

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The GABAA receptor: new insights from single-channel recording

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19447010

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.EPLEPSYRES.2009.03.007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19447010%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19447010%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

19447010

1 reference