t(4;8)(q27;q24) in Hodgkin lymphoma cells targets phosphodiesterase PDE5A and homeobox gene ZHX2. (Q39460302)

12 September 2017

title

t(4;8)(q27;q24) in Hodgkin lymphoma cells targets phosphodiesterase PDE5A and homeobox gene ZHX2. (English)

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12 September 2017

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6

Hans G Drexler

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12 September 2017

3

Andreas Rosenwald

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12 September 2017

Stefan Nagel

1

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12 September 2017

Björn Schneider

2

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12 September 2017

Corinna Meyer

4

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12 September 2017

Maren Kaufmann

5

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12 September 2017

Roderick A F MacLeod

7

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12 September 2017

language of work or name

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30 August 2011

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Genes, Chromosomes and Cancer

12 September 2017

published in

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12 September 2017

volume

50

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12 September 2017

issue

12

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12 September 2017

page(s)

996-1009

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Deregulated homeobox gene expression in cancer: cause or consequence?

12 September 2017

cites work

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Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis

21 January 2018

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The classical Hodgkin's lymphoma microenvironment and its role in promoting tumour growth and immune escape.

21 January 2018

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Low expression of ZHX2, but not RCBTB2 or RAN, is associated with poor outcome in multiple myeloma.

21 January 2018

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STAT6 and STAT1 are essential antagonistic regulators of cell survival in classical Hodgkin lymphoma cell line

21 January 2018

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Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

21 January 2018

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A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3)

21 January 2018

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Detection of genomic imbalances in microdissected Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma by array-based comparative genomic hybridization.

21 January 2018

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Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity

21 January 2018

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21 January 2018

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HES and HERP families: multiple effectors of the Notch signaling pathway

21 January 2018

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Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma.

21 January 2018

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Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor

21 January 2018

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STAT3 is constitutively activated in Hodgkin cell lines

21 January 2018

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Molecular biology of Hodgkin lymphoma

21 January 2018

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Multicolor-FISH analysis of a natural killer cell line (NK-92).

21 January 2018

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Cytogenetic harvesting of commonly used tumor cell lines

21 January 2018

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Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

21 January 2018

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Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity

21 January 2018

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HLXB9 activates IL6 in Hodgkin lymphoma cell lines and is regulated by PI3K signalling involving E2F3.

21 January 2018

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MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines

21 January 2018

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HOX and non-HOX homeobox genes in leukemic hematopoiesis

21 January 2018

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Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing

21 January 2018

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Sildenafil and vardenafil, types 5 and 6 phosphodiesterase inhibitors, induce caspase-dependent apoptosis of B-chronic lymphocytic leukemia cells.

21 January 2018

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Targeting cancer with phosphodiesterase inhibitors

21 January 2018

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IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis

21 January 2018

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Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function

21 January 2018

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The Hox genes and their roles in oncogenesis.

21 January 2018

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Genome-wide copy number analysis of Hodgkin Reed-Sternberg cells identifies recurrent imbalances with correlations to treatment outcome

21 January 2018

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Massive genomic rearrangement acquired in a single catastrophic event during cancer development

21 January 2018

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Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosis.

21 January 2018

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The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension

21 January 2018

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MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival

21 January 2018

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NF-Ya activates multiple hematopoietic stem cell (HSC) regulatory genes and promotes HSC self-renewal

21 January 2018

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Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells

21 January 2018

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Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies

21 January 2018

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Characterization of Early Stages of Human B Cell Development by Gene Expression Profiling

21 January 2018

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Alterations of peripheral blood lymphocyte cyclic AMP and cyclic GMP in untreated patients with hodgkin's disease

21 January 2018

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7 January 2021

Cyclic AMP and cyclic GMP phosphodiesterase activities in Hodgkin's disease lymphocytes

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7 January 2021

Recurring chromosome abnormalities in Hodgkin's disease

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7 January 2021

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7 January 2021

Karyotypic dissection of Hodgkin's disease cell lines reveals ectopic subtelomeres and ribosomal DNA at sites of multiple jumping translocations and genomic amplification

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7 January 2021

Comprehensive analysis of homeobox genes in Hodgkin lymphoma cell lines identifies dysregulated expression of HOXB9 mediated via ERK5 signaling and BMI1.

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7 January 2021

Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

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7 January 2021

Identification of Notch target genes in uncommitted T-cell progenitors: No direct induction of a T-cell specific gene program

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7 January 2021

Identifiers

DOI

10.1002/GCC.20920

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release_tbqwveanfnfwpmae4lqczhh6xm

12 September 2017

Fatcat ID

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