Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1. (Q39427414)

11 September 2017

Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1. (English)

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11 September 2017

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Ai-Luen Wu

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11 September 2017

Ganesh Kolumam

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11 September 2017

Scott Stawicki

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11 September 2017

Yongmei Chen

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11 September 2017

Jun Li

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11 September 2017

Jose Zavala-Solorio

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11 September 2017

Khanhky Phamluong

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11 September 2017

Bo Feng

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11 September 2017

Li Li

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11 September 2017

Scot Marsters

10

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11 September 2017

Lance Kates

11

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11 September 2017

Nicholas van Bruggen

12

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11 September 2017

Maya Leabman

13

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11 September 2017

Anne Wong

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11 September 2017

David West

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11 September 2017

Howard Stern

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11 September 2017

Elizabeth Luis

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11 September 2017

Hok Seon Kim

18

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11 September 2017

Daniel Yansura

19

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11 September 2017

Andrew S Peterson

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11 September 2017

Ellen Filvaroff

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11 September 2017

Yan Wu

22

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11 September 2017

Junichiro Sonoda

23

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11 September 2017

language of work or name

English

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publication date

1 December 2011

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Science Translational Medicine

11 September 2017

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11 September 2017

3

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113

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11 September 2017

113ra126

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FGF-21 as a novel metabolic regulator

11 September 2017

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

FGF21 reloaded: challenges of a rapidly growing field

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Fibroblast growth factor 21 corrects obesity in mice

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Semirational design of a potent, artificial agonist of fibroblast growth factor receptors

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Structural basis for FGF receptor dimerization and activation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Therapeutic antibodies for autoimmunity and inflammation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Inhibition of growth hormone signaling by the fasting-induced hormone FGF21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

C/EBPbeta reprograms white 3T3-L1 preadipocytes to a Brown adipocyte pattern of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Function of mitochondrial Stat3 in cellular respiration

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Thermogenic activation induces FGF21 expression and release in brown adipose tissue.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Monoclonal antibodies: versatile platforms for cancer immunotherapy

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

The FGF23-Klotho axis: endocrine regulation of phosphate homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Function blocking antibodies to neuropilin-1 generated from a designed human synthetic antibody phage library

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

Bivalent antibody phage display mimics natural immunoglobulin

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002669

10.1126/SCITRANSLMED.3002669

21 January 2018

Identifiers

DOI

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11 September 2017

1 reference