Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins. (Q39421660)

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English	Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.	scientific article

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19 January 2020

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins (English)

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19 January 2020

prostate cancer

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Olli-Pekka Kallioniemi

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19 January 2020

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19 January 2020

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19 January 2020

Kristiina Iljin

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Kristiina Iljin

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19 January 2020

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Laura Lehtinen

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19 January 2020

Tuomas Mirtti

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19 January 2020

Mika Hilvo

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19 January 2020

Tuulikki Seppänen-Laakso

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19 January 2020

Johannes Virtanen

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19 January 2020

Anna Sankila

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19 January 2020

Stig Nordling

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19 January 2020

Antti Rannikko

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19 January 2020

Matej Orešič

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19 January 2020

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1 December 2011

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19 January 2020

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19 January 2020

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19 January 2020

12

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19 January 2020

1176-1190

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19 January 2020

Global cancer statistics

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11 September 2017

The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities

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Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition

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Utility of Lp-PLA2 in lipid-lowering therapy

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11 September 2017

Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer.

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11 September 2017

High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer

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11 September 2017

A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses

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11 September 2017

Dietary n-3 polyunsaturated fatty acids fail to reduce prostate tumorigenesis in the PB-ErbB-2 x Pten(+/-) preclinical mouse model

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11 September 2017

ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients' outcome

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11 September 2017

ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells

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11 September 2017

ADP-ribosylation factor 6 regulates tumorigenic and invasive properties in vivo

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11 September 2017

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11 September 2017

Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development

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11 September 2017

Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque

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11 September 2017

Stat3 promotes metastatic progression of prostate cancer.

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11 September 2017

Role of the TMPRSS2-ERG gene fusion in prostate cancer

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11 September 2017

Statin drugs and risk of advanced prostate cancer

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11 September 2017

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

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11 September 2017

Role of lipoprotein-associated phospholipase A2 in atherosclerosis: biology, epidemiology, and possible therapeutic target

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11 September 2017

ALDH activity indicates increased tumorigenic cells, but not cancer stem cells, in prostate cancer cell lines.

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14 September 2017

Statins reduce the androgen sensitivity and cell proliferation by decreasing the androgen receptor protein in prostate cancer cells.

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14 September 2017

FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-to-mesenchymal transition in human prostate cancer cells.

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14 September 2017

Autotaxin promotes cancer invasion via the lysophosphatidic acid receptor 4: participation of the cyclic AMP/EPAC/Rac1 signaling pathway in invadopodia formation

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14 September 2017

Lysophospholipids stimulate prostate cancer cell migration via TRPV2 channel activation

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Statin induces apoptosis and cell growth arrest in prostate cancer cells

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TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming

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14 September 2017

Expression of plasma platelet-activating factor acetylhydrolase is transcriptionally regulated by mediators of inflammation

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25 September 2017

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer

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The phospholipase-A2 reaction leads to increased monocyte adhesion of endothelial cells via the expression of adhesion molecules

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21 August 2018

TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer.

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Lipoprotein-associated phospholipase A2 and its association with cardiovascular outcomes in patients with acute coronary syndromes in the PROVE IT-TIMI 22 (PRavastatin Or atorVastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infar

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21 August 2018

Lipoprotein-associated phospholipase A2 activity is associated with risk of coronary heart disease and ischemic stroke: the Rotterdam Study

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Lipoprotein-associated phospholipase A2 independently predicts the angiographic diagnosis of coronary artery disease and coronary death

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12 December 2020

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Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/22202492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved biochemical outcomes with statin use in patients with high-risk localized prostate cancer treated with radiotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22202492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction by lysophosphatidylcholine, a major phospholipid component of atherogenic lipoproteins, of human coronary artery smooth muscle cell migration

1 reference

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12 December 2020

based on heuristic

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Identifiers

10.18632/ONCOTARGET.397

1 reference

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19 January 2020

1 reference

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19 January 2020

1 reference

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19 January 2020

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