Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1. (Q39418939)

11 September 2017

Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1. (English)

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11 September 2017

Weihong Song

8

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author name string

Mingming Zhang

1

1 reference

11 September 2017

Yu Deng

2

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11 September 2017

Yawen Luo

3

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11 September 2017

Shuting Zhang

4

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11 September 2017

Haiyan Zou

5

1 reference

11 September 2017

Fang Cai

6

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11 September 2017

Keiji Wada

7

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11 September 2017

language of work or name

English

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publication date

10 February 2012

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Journal of Neurochemistry

11 September 2017

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11 September 2017

120

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11 September 2017

6

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11 September 2017

1129-1138

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Mechanism and function of deubiquitinating enzymes

11 September 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

Positive reciprocal regulation of ubiquitin C-terminal hydrolase L1 and beta-catenin/TCF signaling

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1 reference

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BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

21 January 2018

1 reference

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Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.

21 January 2018

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Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.

21 January 2018

1 reference

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Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases

21 January 2018

1 reference

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Mutant ubiquitin expressed in Alzheimer's disease causes neuronal death.

21 January 2018

1 reference

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Cleavage of amyloid beta peptide during constitutive processing of its precursor

21 January 2018

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Presenilin 1 is actively degraded by the 26S proteasome.

21 January 2018

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

21 January 2018

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Ubiquitin hydrolase Uch-L1 rescues beta-amyloid-induced decreases in synaptic function and contextual memory

21 January 2018

1 reference

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Proteomic and histochemical analysis of proteins involved in the dying-back-type of axonal degeneration in the gracile axonal dystrophy (gad) mouse

21 January 2018

1 reference

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Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

21 January 2018

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Ubiquitin-proteasome pathway mediates degradation of APH-1.

21 January 2018

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Degradation of nicastrin involves both proteasome and lysosome

21 January 2018

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21 January 2018

1 reference

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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

21 January 2018

1 reference

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Effect of cycloheximide on protein and ribonucleic acid synthesis in cultured human lymphocytes

21 January 2018

1 reference

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Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome

21 January 2018

1 reference

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Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases

21 January 2018

1 reference

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Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

21 January 2018

1 reference

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The ubiquitin pathway in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

Control of APP processing and Abeta generation level by BACE1 enzymatic activity and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

TMP21 degradation is mediated by the ubiquitin-proteasome pathway

21 January 2018

1 reference

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Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 January 2018

1 reference

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Detection, resolution, and nomenclature of multiple ubiquitin carboxyl-terminal esterases from bovine calf thymus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

Association studies of multiple candidate genes for Parkinson's disease using single nucleotide polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

A genomic and functional inventory of deubiquitinating enzymes

21 January 2018

1 reference

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Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron

21 January 2018

1 reference

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BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

21 January 2018

1 reference

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Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice

21 January 2018

1 reference

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Reduction in memory in passive avoidance learning, exploratory behaviour and synaptic plasticity in mice with a spontaneous deletion in the ubiquitin C-terminal hydrolase L1 gene.

21 January 2018

1 reference

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A polymorphic variation of serine to tyrosine at codon 18 in the ubiquitin C-terminal hydrolase-L1 gene is associated with a reduced risk of sporadic Parkinson's disease in a Japanese population

21 January 2018

1 reference

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Elongin BC complex prevents degradation of von Hippel-Lindau tumor suppressor gene products

21 January 2018

1 reference

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Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 I93M mutant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

Purification and cloning of amyloid precursor protein beta-secretase from human brain

21 January 2018

1 reference

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BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome

21 January 2018

1 reference

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Increased BACE1 maturation contributes to the pathogenesis of Alzheimer's disease in Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kappaB activation.

21 January 2018

1 reference

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2011 Alzheimer's disease facts and figures

21 January 2018

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Recognition of the polyubiquitin proteolytic signal

21 January 2018

1 reference

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A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome

21 January 2018

1 reference

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

NF-κB signaling inhibits ubiquitin carboxyl-terminal hydrolase L1 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

Themes and variations on ubiquitylation

21 January 2018

1 reference

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The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

Gracile axonal dystrophy (GAD), a new neurological mutant in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07644.X

10.1111/J.1471-4159.2011.07644.X

21 January 2018

Identifiers

DOI

1 reference

11 September 2017

1 reference